|   | 
        
            
         | 
          | 
        
        
        
            | 
                
             | 
         
        
             | 
         
        
            
            
            
  
    
	  | 
   
  
    
        
          |   | 
          
              
                | 
                    ¾ÆÀÌÅ©¸°Á¡¾È¾×  [Chloramphenicol , Dexamethasone disodium phosphate , Tetrahydrozoline HCl]  
                    
                 | 
               
              
                | 
                     Àü¹®ÀǾàǰ | »èÁ¦  
                        
                    	
                    
                 | 
               
              
                | 
					  
                  
				  
                 | 
               
              
              
              
              
              |   |  
              
                
                    
                        | 
                      ¾Ë¸²:  | 
                      µå·°ÀÎÆ÷¿¡¼´Â ÀǾàǰ ÀÎÅÍ³Ý ÆÇ¸Å¸¦ ÇÏÁö ¾Ê½À´Ï´Ù. | 
                     
                    | 
               
            
              
                
                   
                   
                   
                   
		   
                 | 
               
              
                | 
                  
                  
                 | 
               
              | 
            | 
         
       
       | 
   
    |  
  
    | 
      
     | 
     
  |  
                              
                                  | 
                                   | 
                               
            
            
                
            
            
              
            
                            
              
                                                     
            
            
   |  
  
    | 
      
     | 
   
   
     | 
   
    
   
    | 
       
        À¯·áȸ¿ø °áÀç½Ã¿¡´Â º¸´Ù ´Ù¾çÇÑ ¾à¹°Á¤º¸¸¦
        ÀÌ¿ëÇÏ½Ç ¼ö ÀÖ½À´Ï´Ù.
        À¯·áÁ¤º¸¸ñ·ÏÀº Àü¹®È¸¿øÀ¸·Î
        ·Î±×ÀÎ ÇϽøé È®ÀÎ °¡´ÉÇÕ´Ï´Ù.
       
     | 
   
  
     | 
   
   
  
    
      
	
	  
	     |  
	    
	      
	        
            
                | Çã°¡Á¤º¸ | 
                         
	         
	       | 
	     
	     |  
	    
  
    | Ç׸ñ | 
    ³»¿ë | 
   
  
   
    û±¸ÄÚµå(KDÄÚµå) ºñ±Þ¿©Á¡°ËÄÚµå  »óÇÑ±Ý¾× | 
    
      
      
        
        642305960[A02550291]  
	    
	    
          [º¸ÇèÄڵ忡 µû¸¥ ¾àǰ±âº»Á¤º¸ Á÷Á¢Á¶È¸] 
          
        
        
        
           \0 ¿ø/1ml(2007.03.01)(ÇöÀç¾à°¡)
            
           \94 ¿ø/1ml(2000.07.01)(º¯°æÀü¾à°¡)
              
	 
	   
	   
       
      
       
       
     
      
      
     
      
    
    
      
     [»óº´ÄÚµåÁ¶È¸]
      
     [Áúº´ÄÚµåÁý ´Ù¿î·Îµå]
     [¿ì¸®Áý°Ç°ÁÖÄ¡ÀÇ ¹Ù·Î°¡±â]
     | 
   
   
    | ºü¸¥Á¶È¸ | 
    
      
     |   
   
  
  
  
  
  
  
  
  
  
  
  
  
  
  	
   
    | ´ëÇ¥ÄÚµå | 
    8806423059609 | 
   
  
  
  
  
  
  
   
    | ¾à¸®ÀÛ¿ë | 
    
      
        [Á¶È¸]
     | 
      
  
  
  
  
   
    | È¿´ÉÈ¿°ú | 
    
    [ÀûÀÀÁõ º° °Ë»ö] 
      
    
     
	 
      1. ½ÉÇÑ ºÎÁ¾°ú Ç¥À缺 ÃæÇ÷À» ¼ö¹ÝÇÏ´Â ¾Ë·¹¸£±â¼º ¶Ç´Â °¨¿°¿¡ ÀÇÇÑ  °¢¸·¿° ¹× °á¸·¿°. 
 2. °ø¸·¿°, »ó°ø¸·¿° 
 3. ȫä¿°, ȫä¸ð¾çü¿°
  
      
      
      
      
     | 
   
  
  
  
  
  
  
  
  
    
  
  
   
    | ¿ë¹ý¿ë·® | 
    
      * Àý´ë ÀÓÀǺ¹¿ëÇÏÁö ¸¶½Ã°í ¹Ýµå½Ã ÀÇ»ç ¶Ç´Â ¾à»ç¿Í »ó´ãÇϽñ⠹ٶø´Ï´Ù. 
    
     
      
      
     [󹿾à¾î] 
      ¼ºÀÎ : 1ȸ 1¹æ¿ï 1ÀÏ 1-4ȸ Á¡¾ÈÇÑ´Ù.      
      	    
     | 
   
  
  
  
  
  
  
  
  
  
   
    | ±Ý±â | 
    
       1) ÀÌ ¾à¿¡ °ú¹ÎÁõ ȯÀÚ 
 2) °¢¸·ÀÌ ¼Õ»óµÇ¾ú°Å³ª ±Ë¾ç ȯÀÚ 
 3) ´Ü¼øÆ÷Áø ¹ÙÀÌ·¯½º ¶Ç´Â µÎâ ¹ÙÀÌ·¯½º °¨¿°Áúȯ ȯÀÚ 
 4) °áÇÙ¼º °¨¿°Áõ, Áø±ÕÁõ, ³ì³»Àå ȯÀÚ 
 5) °á¸· ¹× ¾È°ËÀÇ È³ó¼º °¨¿° ȯÀÚ 
 6) ¾È±¸ °ÇÁ¶Áõ, ƯÈ÷ ¼î±×·» ÁõÈıº ȯÀÚ  
 7) ¼Ò¾Æ 
 8) °íÇ÷¾Ð ¶Ç´Â ÀúÇ÷¾Ð ȯÀÚ 
 9) Àç»ýºÒ·®¼º ºóÇ÷, ¹ü°ñ¼öº´Áõ, ¿ëÇ÷¼º Ȳ´Þ µî ÁßÁõ Ç÷¾× Áúȯ ȯÀÚ 
 10) °£ºÎÀü ȯÀÚ
  
     | 
   
  
  
  
  
   
    | ½ÅÁßÅõ¿© | 
     1) °ü»óµ¿¸Æ Áúȯ ȯÀÚ 
 3) µ¿¸Æ·ù ȯÀÚ 
 4) ½É¹Úµ¿ Àå¾Ö ȯÀÚ 
 5) µ¿¸Æ°æÈ ȯÀÚ 
 6) ´ç´¢º´ ȯÀÚ 
 7) °©»ó¼± ±â´ÉÇ×ÁøÁõ ȯÀÚ 
 8) MAOÀúÇØÁ¦ ¶Ç´Â Ç÷¾Ð»ó½ÂÁ¦¸¦ Åõ¿©ÁßÀΠȯÀÚ
 
  | 
   
  
  
  
   
    | ÀÌ»ó¹ÝÀÀ | 
    
       1) Àå±â°£(3°³¿ù ÀÌ»ó)»ç¿ëÇÒ ¶§ Á¶Ç÷±â´É Àå¾Ö·Î ºñ°¡¿ªÀû ¹üÇ÷±¸°¨¼ÒÁõ ¶Ç´Â Àç»ýºÒ·®¼ººóÇ÷, ¹éÇ÷±¸ °¨¼ÒÁõ, µå¹°°Ô Ç÷¼ÒÆÇ °¨¼ÒÁõÀ» ¾ß±âÇÒ ¼ö ÀÖ´Ù.  
 2) Àå±â°£ »ç¿ëÇÒ ¶§ °¡¿ªÀû ¾È¾Ð»ó½ÂÀ» ÀÏÀ¸Å³ ¼ö ÀÖÀ¸¹Ç·Î ¶§¶§·Î ¾È¾ÐÀ» ÃøÁ¤ÇÒ Çʿ䰡 ÀÖ´Ù. 
 3) Àå±âÅõ¿©½Ã µå¹°°Ô Èij¶ÇϹ鳻ÀåÀÌ »ý±æ ¼ö ÀÖ´Ù 
 4) »óó Ä¡À¯°¡ Áö¿¬µÉ ¼ö ÀÖ´Ù. 
 5) ´«ÀÇ È³ó¼º Áúȯ¿¡¼ ½ºÅ×·ÎÀ̵å´Â °¨¿°À» ÀºÆóÇϰųª ¾ÇȽÃų ¼ö ÀÖ´Ù. 
 6) ½ºÅ×·ÎÀ̵å¿Í Ç×±ÕÁ¦°¡ ÇÔÀ¯µÈ Á¦Á¦ÀÇ »ç¿ëÈÄ¿¡´Â 2Â÷ °¨¿°ÀÌ ³ªÅ¸³¯ ¼ö ÀÖ´Ù. ½ºÅ×·ÎÀ̵åÀÇ Àå±âÅõ¿©½Ã °¢¸·¿¡ Áø±Õ°¨¿°ÀÌ ³ªÅ¸³¯ ¼ö ÀÖÀ¸¸ç Áö¼ÓÀûÀÎ °¢¸·±Ë¾çÀÌ ³ªÅ¸³ª¸é Áø±Õ°¨¿°À» ÀǽÉÇØ¾ßÇÑ´Ù. 
 7) °¢¸· ½ÇÁúÁ¶Á÷ ¹× °ø¸·ÀÌ ¾ã¾ÆÁö´Â Áúȯ¿¡¼ ÀÌ ¾à Åõ¿©½Ã õ°øÀ» ÀÏÀ¸Å³ ¼ö ÀÖ´Ù. 
 8) µå¹°°Ô ½Ã½Å°æ¿°ÀÌ ³ªÅ¸³¯ ¼ö ÀÖ´Ù. 
 9) µå¹°°Ô ¾Ë·¹¸£±â ¹ÝÀÀÀÌ ³ªÅ¸³¯ ¼ö ÀÖ´Ù. 
 10) ¶§¶§·Î Á¡¾È½Ã °æ¹ÌÇÑ ÀÛ¿°¨, Àڱذ¨ÀÌ ÀÖÀ» ¼ö ÀÖ´Ù.  
 11) ¹ÝÀÀ¼º ÃæÇ÷ÀÌ »ý±æ ¼ö ÀÖ´Ù. 
 12) ³ì³»ÀåÀ» À¯¹ßÇÒ ¼ö ÀÖ´Ù. 
 13) ½Ã·ÂÀúÇϰ¡ »ý±æ ¼ö ÀÖ´Ù. 
 14) ºó¸Æ, Ç÷¾Ð»ó½Â, ÁøÀü, µÎÅë, ¹ßÇÑ, ÇÇ·Î, ±ÇÅÂ, ºÒ¸éÁõ µîÀÌ ³ªÅ¸³¯ ¼ö ÀÖ´Ù. 
 15) »ó´çÇÑ °¢¸· ¼Õ»óÀÌ ÀÖ´Â ÀϺΠȯÀÚ¿¡¼ Àλ꿰 ÇÔÀ¯ Á¡¾È¾×ÀÇ »ç¿ë°ú ¿¬°üµÇ¾î °¢¸· ¼®È¸ÈÀÇ »ç·Ê°¡ ¸Å¿ì µå¹°°Ô(0.01% ¹Ì¸¸) º¸°íµÈ ¹Ù ÀÖ´Ù. 
16)ºóµµºÒ¸íÀÇ ½Ã¾ßÈ帲ÀÌ ³ªÅ¸³¯ ¼ö ÀÖ´Ù. 
          
     | 
   
  
  
    
   
    | ÀϹÝÀû ÁÖÀÇ | 
     1) 7-8Àϰ£ »ç¿ëÇÏ¿©µµ Áõ»óÀÇ °³¼±ÀÌ ¾ø´Â °æ¿ì »ç¿ëÀ» ÁßÁöÇϰí ÀÇ»ç ¶Ç´Â ¾à»ç¿Í »óÀÇÇÑ´Ù. 
 2) Ä¡·áÁß¿¡´Â ÄÜÅÃÆ®·»ÁîÀÇ Âø¿ëÀ» ÇÇÇÑ´Ù. 
 3) Á¡¾È½Ã ÀϽÃÀûÀÎ ½Ã·ÂºÒ¼±¸íÀÌ »ý±æ ¼ö ÀÖÀ¸¹Ç·Î ½Ã¾ß°¡ ¼±¸íÇØ Áú ¶§±îÁö ¿îÀüÀ̳ª À§ÇèÇÑ ±â°èÁ¶ÀÛÀ» ÇÏÁö ¾Êµµ·Ï ÁÖÀÇÇÑ´Ù.
  
4)Àü½Å ¹× ±¹¼Ò ÄÚ¸£Æ¼ÄÚ½ºÅ×·ÎÀÌµå »ç¿ëÀ¸·Î ½Ã·ÂÀå¾Ö°¡ º¸°íµÉ ¼ö ÀÖ´Ù. ȯÀÚ¿¡°Ô ½Ã¾ßÈ帲 ¶Ç´Â ±âŸ ½Ã·ÂÀå¾Ö¿Í °°Àº Áõ»óÀÌ ³ªÅ¸³¯ °æ¿ì, ȯÀÚ¸¦ ¾È°úÀǻ翡°Ô º¸³»¾î ¹é³»Àå, ³ì³»Àå ¶Ç´Â Àü½Å ¹× ±¹¼Ò ÄÚ¸£Æ¼ÄÚ½ºÅ×·ÎÀÌµå »ç¿ë ÈÄ º¸°íµÈ Áß½ÉÀå¾×¸Æ¶ô¸Á¸·º´(CSCR)°ú °°Àº Èñ±ÍÁúȯÀ» Æ÷ÇÔÇÏ¿© ¹ß»ý °¡´ÉÇÑ ¿øÀÎ Æò°¡¸¦ °í·ÁÇØ¾ß ÇÑ´Ù.
  
ƯÈ÷ ÀÌ ¾à Åõ¿©Áß¿¡ ¼öµÎ ¶Ç´Â È«¿ª¿¡ °¨¿°µÇ¸é Ä¡¸íÀûÀÎ °æ°ú¿¡ À̸¦ ¼ö ÀÖÀ¸¹Ç·Î ´ÙÀ½ ÁÖÀǰ¡ ÇÊ¿äÇÏ´Ù. 
1) ÀÌ ¾à Åõ¿©Àü¿¡ ¼öµÎ ¶Ç´Â È«¿ªÀÇ º´·Â°ú ¿¹¹æÁ¢Á¾ÀÇ À¯¹«¸¦ È®ÀÎÇÑ´Ù. 
2) ¼öµÎ ¶Ç´Â È«¿ªÀÇ º´·ÂÀÌ ¾ø´Â ȯÀÚ¿¡ ´ëÇØ¼´Â ¼öµÎ ¶Ç´Â È«¿ª¿¡ÀÇ °¨¿°À» ÃÖ´ëÇÑ ¹æÁöÇÏ¿© ÃæºÐÇÑ ¹è·Á¿Í °üÂûÀ» ÇÑ´Ù. °¨¿°ÀÌ Àǽɽº·¯¿î °æ¿ì¿£ Áï½Ã ÁøÂûÀ» ¹Þ¾Æ ÁöµµÇϰí ÀûÀýÇÑ Ã³Ä¡¸¦ ÇÑ´Ù. 
3) ¼öµÎ ¶Ç´Â È«¿ªÀÇ º´·Â°ú ¿¹¹æÁ¢Á¾À» ¹ÞÀº ÀûÀÌ Àִ ȯÀÚ¿¡°Ôµµ ÀÌ ¾à Åõ¿©Áß¿¡ ¼öµÎ ¶Ç´Â È«¿ªÀÌ ³ªÅ¸³¯ °¡´É¼ºÀÌ ÀÖÀ¸¹Ç·Î À¯ÀÇÇÑ´Ù.
 
  | 
   
  
  
  
    
   
    | »óÈ£ÀÛ¿ë | 
    ¾ÆÆ®·ÎÇÉ µî Ç×Äݸ°Á¦¿Í º´¿ëÅõ¿©½Ã ¾È¾ÐÀÌ »ó½ÂµÉ ¼ö ÀÖ´Ù.
 
  | 
   
  
  
  
   
    | ÀӺο¡ ´ëÇÑ Åõ¿© | 
    
      
	[ÀӺαݱ⠼ººÐ Á¶È¸]       
      µ¿¹°½ÃÇè¿¡¼ ÅÂÀÚ µ¶¼º ¹× ¼Õ»óÀÌ °üÂûµÇ¾úÀ¸¸ç ÀÓ½ÅÁßÀÇ Åõ¿©¿¡ ´ëÇÑ ¾ÈÀü¼ºÀÌ È®¸³µÇ¾î ÀÖÁö ¾ÊÀ¸¹Ç·Î ÀӺΠ¶Ç´Â ÀÓ½ÅÇϰí ÀÖÀ» °¡´É¼ºÀÌ ÀÖ´Â ºÎÀο¡´Â Ä¡·á»óÀÇ À¯ÀͼºÀÌ À§Ç輺À» »óȸÇÑ´Ù°í ÆÇ´ÜµÇ´Â °æ¿ì¿¡¸¸ Åõ¿©ÇÑ´Ù.
  
     | 
   
  
  
  
  
   
    | ¼öÀ¯ºÎ¿¡ ´ëÇÑ Åõ¿© | 
    ¸ðÀ¯·ÎÀÇ ÀÌÇà¿©ºÎ´Â ¾Ë·ÁÁöÁö ¾Ê¾ÒÀ¸³ª ¼öÀ¯ºÎ¿¡ Åõ¿©ÇÏ´Â °æ¿ì ¿µ¾Æ¿¡ ´ëÇÑ ¾ÈÀü¼ºÀÌ È®¸³µÇ¾î ÀÖÁö ¾ÊÀ¸¹Ç·Î ¼öÀ¯ºÎ¿¡´Â Åõ¿©ÇÏÁö ¸»°í ºÎµæÀÌ Åõ¿©ÇÏ´Â °æ¿ì¿¡´Â ¼öÀ¯¸¦ Áß´ÜÇÑ´Ù.
 
  | 
   
  
  
  
  
   
    | ¼Ò¾Æ¿¡ ´ëÇÑ Åõ¿© | 
    
      
       
      ¼Ò¾Æ¿¡ ´ëÇÑ Åõ¿©
 ¼Ò¾Æ¿¡ ´ëÇÑ ¾ÈÀü¼º ¹× À¯È¿¼ºÀÌ È®¸³µÇ¾î ÀÖÁö ¾Ê´Ù.
 
  | 
   
  
  
  
  
  
  
  
  
  
  
  
    
   
    | Àû¿ë»óÀÇ ÁÖÀÇ | 
     1) Á¡¾È¿ëÀ¸·Î¸¸ »ç¿ëÇÑ´Ù. 
 2) Á¡¾È½Ã ¿ë±âÀÇ ÀÔ±¸°¡ Á÷Á¢ ´«¿¡ ´êÁö ¾Êµµ·Ï ÁÖÀÇÇÑ´Ù. 
 3) ¿À¿°À» ¹æÁöÇϱâ À§ÇØ µÉ ¼ö ÀÖ´Â ÇÑ °øµ¿À¸·Î »ç¿ëÇÏÁö ¾Ê´Â´Ù.
 
  | 
   
  
  
  
  
  
  		
  
  
   
    | º¸°ü ¹× Ãë±Þ»óÀÇ ÁÖÀÇ | 
     1) ¼Ò¾ÆÀÇ ¼ÕÀÌ ´êÁö ¾Ê´Â °÷¿¡ º¸°üÇÑ´Ù. 
 2) Á÷»çÀϱ¤À» ÇÇÇÏ°í µÇµµ·Ï(½À±â°¡ ÀûÀº)¼´ÃÇÑ °÷¿¡ »ç¿ëÈÄ ¶Ñ²±À» Àß ´Ý¾Æ º¸°üÇÑ´Ù[°ýÈ£³»´Â ÇÊ¿ä½Ã¿¡ ±âÀçÇÑ´Ù.]. 
 3) ¿À¿ëÀ» ¸·°í ǰÁúÀÇ º¸Á¸À» À§ÇÏ¿© ´Ù¸¥ ¿ë±â¿¡ ¹Ù²Ù¾î ³ÖÁö ¾Ê´Â´Ù.
 
  | 
   
  	
  
  
  
  
  
  
   
    | Related FDA Approved Drug | 
    
       
     | 
      
  
  
      							
 
 |  
	   
	 
	
	  
       |  
	    
	      
	        
            
                | Á¤º¸¿ä¾à | 
                 
	         
	       | 
	           	    
	     |  
	    | 
  
    µå·°ÀÎÆ÷ ÀǾàǰ ¿ä¾à/»ó¼¼Á¤º¸
    
  
  
    
  
   |  
	   
	 
	
	  
       |  
	    
	      
	        
            
                | ÄÚµå ¹× ºÐ·ùÁ¤º¸ | 
                 
	         
	       | 
	           	    
	     |  
	    | 	 |  
	   
	 
	
	  
       |  
	    
	      
	        
            
                | Á¦Ç°Á¤º¸ | 
                             
	         
	       | 
	           	  
	     |  
	     |  
	   
	 
	
	  
       |  
	    
	      
	        
            
                | º¹¾àÁ¤º¸ | 
                             
	         
	       | 
	           	  
	     |  
	    
  
    | Ç׸ñ | 
    ³»¿ë | 
   
   
    | LACTmed ¹Ù·Î°¡±â | 
    
      
        [¹Ù·Î°¡±â]
     | 
     
  
  
   
    | ¾à¸®ÀÛ¿ë | 
    
       
      À¯·áÁ¤º¸ÀÔ´Ï´Ù.
       
     | 
     
  
  
  
   
    | Ãà¾àº¹¾àÁöµµ | 
    
     
    À¯·áÁ¤º¸ÀÔ´Ï´Ù.
    
     | 
   
       
  
  
   
    | º¹¾àÁöµµ | 
    
     
    À¯·áÁ¤º¸ÀÔ´Ï´Ù.
    
     | 
   
                                                          															
  
   
  
  
   
    | ÀӺο¡´ëÇÑÅõ¿© | 
    
      
      
        
	      
	      
	        | *  | 
	        
	          ÀüüÀӽŠ±â°£º°·Î ¿©·¯µî±ÞÀÌ Á¸ÀçÇÒ ¼ö ÀÖÀ¸¸ç °¡Àå À§Çèµµ°¡ ³ôÀº Á¤º¸¸¸ º¸¿©Áý´Ï´Ù. ´Ü, º¹ÇÕÁ¦ÀÇ °æ¿ì ¸ðµç º¹ÇÕÁ¦¼ººÐ¿¡ ´ëÇÑ ÀÓºÎÅõ¿©µî±ÞÀÌ Ç¥½ÃµÈ°ÍÀº Àý´ë ¾Æ´Ï¸ç Ç¥½ÃµÈ°ÍÁß¿¡ °¡Àå À§Çèµµ°¡ ³ôÀº Á¤º¸¸¸ ³ªÅ¸³³´Ï´Ù. 
	         | 
	         
	       
	       | 
	   
	  
	    |   | 
	   
	  
	    
	      FDA : Cµî±Þ 
				        
				         (chloramphenicol;dexamethasone; )
				        
	   | 
	  
	  
	  
	     
	     
	     
	     
	     
	     
	   | 
	 
	
	  
	      
	      
	        | *  | 
	        
	          »ó±â ÀÓºÎÅõ¿©¿¡ ´ëÇÑ Á¤º¸´Â Àü»êó¸® µÇ¸é¼ ÀÔ·Â ¿À·ù °¡´É¼ºÀÌ Á¸ÀçÇÕ´Ï´Ù. ¿À·ù °¡´É¼ºÀ» ÃÖ¼ÒÈÇϱâ À§ÇÏ¿© ¸¹Àº ³ë·ÂÀ» ±â¿ïÀ̰í ÀÖÀ¸³ª, ±× Á¤È®¼º¿¡ ´ëÇÏ¿© È®½ÅÀ» µå¸± ¼ö ¾ø½À´Ï´Ù. ÀÌ¿¡ ´ëÇØ ȸ»ç´Â Ã¥ÀÓÀ» ÁöÁö ¾Ê½À´Ï´Ù.
	         | 
	         
	      
	        | *  | 
	        
	          ¹Ýµå½Ã °ø½Å·Â ÀÖ´Â ¹®ÇåÀ» ´Ù½Ã Çѹø Âü°í ÇϽñ⠹ٶó¸ç ÀÇ»ç ¶Ç´Â ¾à»çÀÇ ÆÇ´Ü¿¡ µû¶ó Åõ¿©¿©ºÎ°¡ °áÁ¤µÇ¾î¾ß ÇÕ´Ï´Ù.
	         | 
	         
	       
	   | 
	 
       
     | 
   
  
  
  
   
    ½ÅÀå¾Ö, °£Àå¾Ö½Ã ¿ë·®Á¶Àý | 
    
     
    À¯·áÁ¤º¸ÀÔ´Ï´Ù.
    
     | 
   
  	   
  
  	   
  
  	   
  
  
     
      | Pharmacokinetics | 
      
       
      À¯·áÁ¤º¸ÀÔ´Ï´Ù.
      
       |   
     
  
  
  
  
  
  
  
   
    | º´¿ë±Ý±â ¹× ¿¬·É´ë±Ý±â ±Ù°ÅÁ¶È¸ | 
    
      [º´¿ë±Ý±â ¹× ¿¬·É´ë±Ý±â ±Ù°ÅÁ¶È¸]
     | 
   
  	
  
  
  	
  
  
   
    | Á¦Çüº° º¹¾àÁöµµ | 
    [Á¡¾È¾×] | 
   
  
  
   
    | º¸°ü»ó ÁÖÀÇ | 
    
      
    	
     | 
   
  
  
   
    | Á¶Á¦½Ã ÁÖÀÇ | 
    
      
    	
     | 
      
 
 |  
	   
	 
	
	  
       |  
	    
	      
	        
            
                | ½É»çÁ¤º¸ | 
                             
	         
	       | 
	           	  
	     |  
	     |  
	   
	   
	
	  
       |  
	    
	      
	        
            
                | ÇмúÁ¤º¸ | 
                             
	         
	       | 
	           	  
	     |  
	    
  
    | Ç׸ñ | 
    ³»¿ë | 
   
  
    | DUR (ÀǾàǰ»ç¿ëÆò°¡) | 
    º´¿ë±Ý±â :
     
	 °í½ÃµÈ º´¿ë±Ý±â ³»¿ëÀº ¾ø½À´Ï´Ù.
	 
	  [»óÈ£ÀÛ¿ë/º´¿ë±Ý±â°Ë»ö]										
	  ¿¬·É´ë±Ý±â :
      °í½ÃµÈ ¿¬·É±Ý±â ³»¿ëÀº ¾ø½À´Ï´Ù.
      
       [¿¬·É´ë±Ý±â»ó¼¼°Ë»ö]
       
       
        
        
     | 
   
  
   
    | µ¶¼ºÁ¤º¸ | 
    Chloramphenicol¿¡ ´ëÇÑ µ¶¼ºÁ¤º¸ : Á¤º¸º¸±â 
Dexamethasone¿¡ ´ëÇÑ µ¶¼ºÁ¤º¸ : Á¤º¸º¸±â 
  Ãâó: ±¹¸³µ¶¼º°úÇпø µ¶¼º¹°ÁúÁ¤º¸DB : http://www.nitr.go.kr/nitr/contents/m134200/view.do  | 
   
  
   
    | Mechanism of Action | 
    
       Chloramphenicol¿¡ ´ëÇÑ Mechanism_Of_Action Á¤º¸ Chloramphenicol is lipid-soluble, allowing it to diffuse through the bacterial cell membrane. It then reversibly binds to the 50S subunit of bacterial ribosomes where transfer of amino acids to growing peptide chains is prevented (perhaps by suppression of peptidyl transferase activity), thus inhibiting peptide bond formation and subsequent protein synthesis.
  Dexamethasone¿¡ ´ëÇÑ Mechanism_Of_Action Á¤º¸ Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic receptors. This results in a modification of transcription and, hence, protein synthesis in order to achieve inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of dexamethasone are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. 
     | 
   
  
   
    | Pharmacology | 
     
       Chloramphenicol¿¡ ´ëÇÑ Pharmacology Á¤º¸ Chloramphenicol is a broad-spectrum antibiotic that was derived from the bacterium Streptomyces venezuelae and is now produced synthetically. Chloramphenicol is effective against a wide variety of microorganisms, but due to serious side-effects (e.g., damage to the bone marrow, including aplastic anemia) in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., typhoid fever). Chloramphenicol is bacteriostatic but may be bactericidal in high concentrations or when used against highly susceptible organisms. Chloramphenicol stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis.
  Dexamethasone¿¡ ´ëÇÑ Pharmacology Á¤º¸ Dexamethasone and its derivatives, dexamethasone sodium phosphate and dexamethasone acetate, are synthetic glucocorticoids. Used for its antiinflammatory or immunosuppressive properties and ability to penetrate the CNS, dexamethasone is used alone to manage cerebral edema and with tobramycin to treat corticosteroid-responsive inflammatory ocular conditions. 
     | 
   
  
   
    | Metabolism | 
    
       Chloramphenicol¿¡ ´ëÇÑ Metabolism Á¤º¸ # Phase_1_Metabolizing_Enzyme:Not Available
  Dexamethasone¿¡ ´ëÇÑ Metabolism Á¤º¸ # Phase_1_Metabolizing_Enzyme:Cytochrome P450 3A4 (CYP3A4) 
     | 
   
  
   
    | Protein Binding | 
    
       Chloramphenicol¿¡ ´ëÇÑ ´Ü¹é°áÇÕ Á¤º¸ Plasma protein binding is 50-60% in adults and 32% is premature neonates.
  Dexamethasone¿¡ ´ëÇÑ ´Ü¹é°áÇÕ Á¤º¸ 70% 
     | 
   
  
   
    | Half-life | 
    
       Chloramphenicol¿¡ ´ëÇÑ ¹Ý°¨±â Á¤º¸ Half-life in adults with normal hepatic and renal function is 1.5 - 3.5 hours. In patients with impaired renal function half-life is 3 - 4 hours. In patients with severely impaired hepatic function half-life is 4.6 - 11.6 hours. Half-life in children 1 month to 16 years old is 3 - 6.5 hours, while half-life in infants 1 to 2 days old is 24 hours or longer and is highly variable, especially in low birth-weight infants.
  Dexamethasone¿¡ ´ëÇÑ ¹Ý°¨±â Á¤º¸ 36-54 hours 
     | 
   
  
   
    | Absorption | 
    
       Chloramphenicol¿¡ ´ëÇÑ Absorption Á¤º¸ Rapidly and completely absorbed from gastrointestinal tract following oral administration (bioavailability 80%). Well absorbed following intramuscular administration (bioavailability 70%). Intraocular and some systemic absorption also occurs after topical application to the eye.
  Dexamethasone¿¡ ´ëÇÑ Absorption Á¤º¸ 80-90% 
     | 
   
  
   
    | Pharmacokinetics | 
    
       Dexamethasone disodium phosphateÀÇ ¾à¹°µ¿·ÂÇÐÀÚ·á 
	- ´ë»çÈ¿°ú Áö¼Ó½Ã°£ : 72½Ã°£±îÁö Áö¼ÓµÉ ¼ö ÀÖ´Ù. Acetate´Â ÀÛ¿ë ¹ßÇö ½Ã°£À» ÃËÁø½ÃŲ Àå½Ã°£ Áö¼ÓÇü repository Á¦Á¦ÀÌ´Ù.
	
 - ´ë»ç : °£¿¡¼ ´ë»ç
	
 - ¹Ý°¨±â 
	
		-  Á¤»ó ½Å±â´É : 1.8¡3.5½Ã°£
		
 -  »ý¸®Àû ¹Ý°¨±â : 36¡54½Ã°£
	
  
	 - ÃÖ´ëÈ¿°ú ¹ßÇö½Ã°£
	
		-  °æ±¸ : 1¡2½Ã°£ À̳»
		
 -  ±ÙÀ°ÁÖ»ç : 8½Ã°£ À̳»
	
  
	 - ¼Ò½Ç : ´¢³ª º¯À¸·Î ¹è¼³
  
 ChloramphenicolÀÇ ¾à¹°µ¿·ÂÇÐÀÚ·á 
-  Èí¼ö : ½Å»ý¾Æ : À§Àå°ü Èí¼ö°¡ ´À¸®°í ºÒ±ÔÄ¢ÇÏ´Ù.
 -  »ýü³»ÀÌ¿ë·ü : °æ±¸ : 75-100%
 -  ºÐÆ÷ : ¿ëÀÌÇÏ°Ô Å¹ÝÅë°ú, À¯ÁóºÐºñ, ´ëºÎºÐÀÇ Á¶Á÷¿Í ü¾×¿¡ ³Î¸® ºÐÆ÷
	
	-  ³úô¼ö¾×À¸·ÎÀÇ ºÐÆ÷ : ¿°Áõ¿¡ °ü°è¾øÀÌ ³úô¼ö¾×À¸·Î Àß À̵¿µÈ´Ù. (MIC ÀÌ»ó)
		
		-  Á¤»ó ³ú¸· : 66%
		
 -  ³ú¼ö¸·¿° : 66 %ÀÌ»ó 
		
  
	  
 -  ´Ü¹é°áÇÕ : 60%
 -  ´ë»ç : 
	
	-  90%°¡ °£¿¡¼ ÁÖ·Î glucuronidation¿¡ ÀÇÇØ ºÒȰ¼ºÈµÈ´Ù.
	
 -  Chloramphenicol palmitate : À§Àå°ü¿¡¼ lipase¿¡ ÀÇÇØ Ȱ¼º´ë»çü·Î °¡¼öºÐÇØµÈ´Ù.
	
 -  Chloramphenicol sodium succinate : esterase¿¡ ÀÇÇØ Ȱ¼º´ë»çü·Î °¡¼öºÐÇØµÈ´Ù.
	
  
 -  ¹Ý°¨±â : 
	
	-  ƯÈ÷ °£±â´É ºÎÀü ¶Ç´Â °£/½Å±â´É ºÎÀüÀÌ °°ÀÌ ¹ß»ýÇßÀ» ¶§ ¿¬ÀåµÈ´Ù.
	
 -  Á¤»ó ½Å±â´É : 1.6-3.3 ½Ã°£ 
	
 -  ¸»±â½ÅºÎÀü : 3-7 ½Ã°£
	
 -  °£°æº¯ : 10-12 ½Ã°£
	
 -  ½Å»ý¾Æ : 
		
		-  »ýÈÄ 1-2ÀÏ : 24½Ã°£
		
 -  »ýÈÄ 10-16ÀÏ : 10½Ã°£
		
  
	  
 -  Ç÷ÁßÃÖ°í³óµµ µµ´Þ½Ã°£ : °æ±¸ : 0.5-3 ½Ã°£ À̳»
 -  ¼Ò½Ç : 
	
	-  5-15%°¡ ¹Ìº¯Èü·Î ½Å¹è¼³, 4%°¡ ´ãÁó ¹è¼³
	
 -  ½Å»ý¾Æ : 6-80%°¡ ¹Ìº¯Èü·Î ½Å¹è¼³
	
  
  
 Tetrahydrozoline HClÀÇ ¾à¹°µ¿·ÂÇÐÀÚ·á 
	- ÃæÇ÷Á¦°ÅÈ¿°ú ¹ßÇö½Ã°£ : ºñ°³» Åõ¿© : 4-8 ½Ã°£ À̳»
	
 - ÀÛ¿ëÁö¼Ó½Ã°£ : ¾ÈÇ÷°ü ¼öÃà : 2-3 ½Ã°£
	
 - Èí¼ö : ±¹¼Ò : ¶§·Î Àü½Å Èí¼ö°¡ ³ªÅ¸³².
  
     | 
   
  
   
    | Biotransformation | 
    
       Chloramphenicol¿¡ ´ëÇÑ Biotransformation Á¤º¸ Hepatic, with 90% conjugated to inactive glucuronide.
  Dexamethasone¿¡ ´ëÇÑ Biotransformation Á¤º¸ Hepatic. 
     | 
   
  
   
    | Toxicity | 
    
       Chloramphenicol¿¡ ´ëÇÑ Toxicity Á¤º¸ Oral, mouse: LD50 = 1500 mg/kg; Oral, rat: LD50 = 2500 mg/kg. Toxic reactions including fatalities have occurred in the premature and newborn; the signs and symptoms associated with these reactions have been referred to as the gray syndrome. Symptoms include (in order of appearance) abdominal distension with or without emesis, progressive pallid cyanosis, vasomotor collapse frequently accompanied by irregular respiration, and death within a few hours of onset of these symptoms.
  Dexamethasone¿¡ ´ëÇÑ Toxicity Á¤º¸ Oral, rat LD50: >3 gm/kg. Signs of overdose include retinal toxicity, glaucoma, subcapsular cataract, gastrointestinal bleeding, pancreatitis, aseptic bone necrosis, osteoporosis, myopathies, obesity, edemas, hypertension, proteinuria, diabetes, sleep disturbances, psychiatric syndromes, delayed wound healing, atrophy and fragility of the skin, ecchymosis, and pseudotumor cerebri. 
     | 
   
  
   
    | Drug Interactions | 
    
       Chloramphenicol¿¡ ´ëÇÑ Drug_Interactions Á¤º¸ Acetohexamide	The agent increases the effect of sulfonylureaAnisindione	Increases the anticoagulant effectChlorpropamide	The agent increases the effect of sulfonylureaCyclosporine	Increases the effect of cyclosporineDicumarol	Increases the anticoagulant effectEthotoin	Increases phenytoin, modifies chloramphenicolFosphenytoin	Increases phenytoin, modifies chloramphenicolGliclazide	The agent increases the effect of sulfonylureaGlipizide	The agent increases the effect of sulfonylureaGlisoxepide	The agent increases the effect of sulfonylureaGlibenclamide	The agent increases the effect of sulfonylureaGlycodiazine	The agent increases the effect of sulfonylureaMephenytoin	Increases phenytoin, modifies chloramphenicolAcenocoumarol	Increases the anticoagulant effectPhenytoin	Increases phenytoin, modifies chloramphenicolRifampin	Rifampin decreases the effect of chloramphenicolTacrolimus	Increases tacrolimus levelsTolazamide	The agent increases the effect of sulfonylureaTolbutamide	The agent increases the effect of sulfonylureaWarfarin	Increases the anticoagulant effect
  Dexamethasone¿¡ ´ëÇÑ Drug_Interactions Á¤º¸ Ambenonium	The corticosteroid decreases the effect of anticholinesterasesAminoglutethimide	Aminogluthetimide decreases the effect of dexamethasoneAmobarbital	The barbiturate decreases the effect of the corticosteroidAnisindione	The corticosteroid alters the anticoagulant effectAprepitant	Aprepitant increases the effect and toxicity of dexamethasoneAprobarbital	The barbiturate decreases the effect of the corticosteroidAspirin	The corticosteroid decreases the effect of salicylatesButabarbital	The barbiturate decreases the effect of the corticosteroidButalbital	The barbiturate decreases the effect of the corticosteroidButethal	The barbiturate decreases the effect of the corticosteroidDicumarol	The corticosteroid alters the anticoagulant effectDihydroquinidine barbiturate	The barbiturate decreases the effect of the corticosteroidEdrophonium	The corticosteroid decreases the effect of anticholinesterasesEthotoin	The enzyme inducer decreases the effect of the corticosteroidFosphenytoin	The enzyme inducer decreases the effect of the corticosteroidHeptabarbital	The barbiturate decreases the effect of the corticosteroidHexobarbital	The barbiturate decreases the effect of the corticosteroidImatinib	Decreases levels of imatinibMephenytoin	The enzyme inducer decreases the effect of the corticosteroidMethohexital	The barbiturate decreases the effect of the corticosteroidMethylphenobarbital	The barbiturate decreases the effect of the corticosteroidMidodrine	Increased arterial pressureNeostigmine	The corticosteroid decreases the effect of anticholinesterasesPentobarbital	The barbiturate decreases the effect of the corticosteroidPhenobarbital	The barbiturate decreases the effect of the corticosteroidPhenytoin	The enzyme inducer decreases the effect of the corticosteroidPrimidone	The barbiturate decreases the effect of the corticosteroidPyridostigmine	The corticosteroid decreases the effect of anticholinesterasesQuinidine barbiturate	The barbiturate decreases the effect of the corticosteroidRifampin	The enzyme inducer decreases the effect of the corticosteroidSecobarbital	The barbiturate decreases the effect of the corticosteroidSunitinib	Possible decrease in sunitinib levelsTalbutal	The barbiturate decreases the effect of the corticosteroidWarfarin	The corticosteroid alters the anticoagulant effectBismuth	The corticosteroid decreases the effect of salicylatesAcenocoumarol	The corticosteroid alters the anticoagulant effectSalicylate-magnesium	The corticosteroid decreases the effect of salicylatesSalsalate	The corticosteroid decreases the effect of salicylates 
     | 
   
  
   
    CYP450  Drug Interaction | 
    
      [CYP450 TableÁ÷Á¢Á¶È¸] 
     | 
   
  
   
    | Food Interaction | 
    
       Chloramphenicol¿¡ ´ëÇÑ Food Interaction Á¤º¸ Take on an empty stomach.
  Dexamethasone¿¡ ´ëÇÑ Food Interaction Á¤º¸ Avoid alcohol.Take with food to reduce irritation.Avoid taking with grapefruit juice. 
     | 
   
  
   
    | Drug Target | 
    
      
      [Drug Target]
     | 
   
  
   
    | Description | 
    
       Chloramphenicol¿¡ ´ëÇÑ Description Á¤º¸ An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
  Dexamethasone¿¡ ´ëÇÑ Description Á¤º¸ An anti-inflammatory 9-fluoro-glucocorticoid. [PubChem] 
     | 
   
  
   
    | Drug Category | 
    
       Chloramphenicol¿¡ ´ëÇÑ Drug_Category Á¤º¸ Anti-Bacterial AgentsProtein Synthesis Inhibitors
  Dexamethasone¿¡ ´ëÇÑ Drug_Category Á¤º¸ Adrenergic AgentsAnti-inflammatory AgentsAntiemeticsAntineoplastic Agents, HormonalGlucocorticoids 
     | 
   
  
   
    | Smiles String Canonical | 
    
       Chloramphenicol¿¡ ´ëÇÑ Smiles_String_canonical Á¤º¸ OCC(NC(=O)C(Cl)Cl)C(O)C1=CC=C(C=C1)[N+]([O-])=O
  Dexamethasone¿¡ ´ëÇÑ Smiles_String_canonical Á¤º¸ CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO 
     | 
   
  
   
    | Smiles String Isomeric | 
    
       Chloramphenicol¿¡ ´ëÇÑ Smiles_String_isomeric Á¤º¸ OC[C@H](NC(=O)C(Cl)Cl)[C@@H](O)C1=CC=C(C=C1)[N+]([O-])=O
  Dexamethasone¿¡ ´ëÇÑ Smiles_String_isomeric Á¤º¸ C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 
     | 
   
  
   
    | InChI Identifier | 
    
       Chloramphenicol¿¡ ´ëÇÑ InChI_Identifier Á¤º¸ InChI=1/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/f/h14H
  Dexamethasone¿¡ ´ëÇÑ InChI_Identifier Á¤º¸ InChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 
     | 
   
  
   
    | Chemical IUPAC Name | 
    
       Chloramphenicol¿¡ ´ëÇÑ Chemical_IUPAC_Name Á¤º¸ 2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
  Dexamethasone¿¡ ´ëÇÑ Chemical_IUPAC_Name Á¤º¸ (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 
     | 
   
  
   
    | Drug-Induced Toxicity Related Proteins | 
    
      DEXAMETHASONE ÀÇ Drug-Induced Toxicity Related ProteinÁ¤º¸ Replated Protein:Brain-cadherin (BR-cadherin) Drug:dexamethasone Toxicity:osteoblast differentiation.  [¹Ù·Î°¡±â] Replated Protein:Glucocorticoid-induced leucine zipper (GILZ) Drug:dexamethasone Toxicity:apoptosis.  [¹Ù·Î°¡±â] Replated Protein:Signal transducer and activator of transcription 3 Drug:dexamethasone Toxicity:apoptosis.  [¹Ù·Î°¡±â] Replated Protein:Heme oxygenase 1 Drug:dexamethasone Toxicity:oxidative injury.  [¹Ù·Î°¡±â] Replated Protein:Alkaline phosphatase Drug:dexamethasone Toxicity:osteoblast differentiation.  [¹Ù·Î°¡±â] Replated Protein:Interleukin-6  Drug:dexamethasone Toxicity:apoptosis.  [¹Ù·Î°¡±â] Replated Protein:Ornithine decarboxylase  Drug:dexamethasone Toxicity:pathogenesis of peptic ulcers.  [¹Ù·Î°¡±â] Replated Protein:Aromatic-L-amino-acid decarboxylase  Drug:dexamethasone Toxicity:pathogenesis of peptic ulcers.  [¹Ù·Î°¡±â] Replated Protein:Interleukin-4  Drug:dexamethasone Toxicity:dexamethasone-induced differentiation of mouse myeloid leukemia cells.  [¹Ù·Î°¡±â] Replated Protein:Gastrin Drug:dexamethasone Toxicity:pathogenesis of peptic ulcers.  [¹Ù·Î°¡±â] Replated Protein:Interleukin-4  Drug:dexamethasone Toxicity:dexamethasone-induced differentiation of mouse myeloid leukemia cells.  [¹Ù·Î°¡±â] Replated Protein:Cadherin-11  Drug:dexamethasone Toxicity:osteoblast differentiation.  [¹Ù·Î°¡±â] Replated Protein:Haptoglobin  Drug:dexamethasone Toxicity:hepatic lipidosis(fatty liver).  [¹Ù·Î°¡±â] Replated Protein:Interferon alpha-7  Drug:dexamethasone Toxicity:apoptosis.  [¹Ù·Î°¡±â] Replated Protein:C-jun-amino-terminal kinase-interacting protein  Drug:dexamethasone Toxicity:apoptosis of multiple myeloma cells.  [¹Ù·Î°¡±â] Replated Protein:Mitogen-activated protein kinase Drug:dexamethasone Toxicity:Dex-induced apoptosis.  [¹Ù·Î°¡±â] Replated Protein:Cadherin-4  Drug:dexamethasone Toxicity:osteoblast differentiation.  [¹Ù·Î°¡±â] Replated Protein:Glucose transporter 4 Drug:dexamethasone Toxicity:cushing's syndrome.  [¹Ù·Î°¡±â] Replated Protein:Nuclear factor NF-kappa-B Drug:dexamethasone Toxicity:pulmonary inflammation.  [¹Ù·Î°¡±â] Replated Protein:Signal transducer and activator of transcription 3 Drug:dexamethasone Toxicity:oxidative injury such as endotoxins and heme.  [¹Ù·Î°¡±â] Replated Protein:Thrombomodulin  Drug:dexamethasone  Toxicity:deep venous thrombosis (DVT).  [¹Ù·Î°¡±â] Replated Protein:Islet amyloid polypeptide Drug:dexamethasone  Toxicity:marked stimulatory effect.  [¹Ù·Î°¡±â] 
     | 
   
    
  |  
	   
	   
	
	  
       |  
	    
	      
	        
            
                | »ç¿ëÀÚÄÁÅÙÃ÷ | 
                             
	         
	       | 
	           	  
       |  
	     |  
	   
	     	
 
  | 
   
   
     | 
   
  
    
      
        
          
            
              - 
                ÃÖ±ÙÁ¤º¸¼öÁ¤ÀÏ 2025-11-03
              
 
              - 
                
                º» ¼öÁ¤ÀÏ Á¤º¸´Â Çã°¡Á¤º¸ ÀÌ¿ÜÀÇ ±âŸÁ¤º¸ ¼öÁ¤ÀÏÀ» ÀǹÌÇϹǷÎ, Çã°¡Á¤º¸¼öÁ¤ÀÏÀº º»¹®¿¡ Ç¥±âµÈ ³¯Â¥¸¦ ÂüÁ¶ÇϽñ⠹ٶø´Ï´Ù.
                
              
     
             
         |                 
       
     |       
          
                
                    
                       ¾Ë¸² | 
                       
                      »ó¼¼Á¤º¸´Â ½ÄǰÀǾàǰ¾ÈÀüóÀÇ Á¦Ç°Çã°¡»çÇ×À» Åä´ë·Î ÀÛ¼ºµÇ¾úÀ¸¸ç ¿ä¾àÁ¤º¸´Â »ó¼¼Á¤º¸ ¹× ±âŸ¹®ÇåÀ» ±â¹ÝÀ¸·Î µå·°ÀÎÆ÷¿¡¼ ÆíÁýÇÑ ³»¿ëÀÔ´Ï´Ù. Á¦Ç°Çã°¡»çÇ×ÀÇ ¸ñÂ÷¿Í ´Ù¼Ò »óÀÌÇÒ ¼ö ÀÖ½À´Ï´Ù.  | 
                    
                    | 
               
      
      
                
                    
                       °æ°í | 
                     
                      µå·°ÀÎÆ÷ ÀǾàÇмúÁ¤º¸´Â ½ÄǰÀǾàǰ¾ÈÀüóÀÇ Á¦Ç°Çã°¡»çÇ×, Çмú¹®Çå, Á¦¾àȸ»ç Á¦°øÁ¤º¸ µîÀ» ±Ù°Å·Î ÀÛ¼ºµÈ Âü°í Á¤º¸ÀÔ´Ï´Ù. 
                          Á¤º¸ÀÇ Á¤È®¼ºÀ» À§ÇØ ³ë·ÂÇϰí ÀÖÀ¸³ª ÆíÁý»óÀÇ ¿À·ù, Çã°¡»çÇ× º¯°æ, Ãß°¡ÀûÀÎ Çмú¿¬±¸ ¶Ç´Â Àӻ󿬱¸ ¹ßÇ¥ µîÀ¸·Î ÀÎÇØ ¹ß»ýÇÏ´Â ¹®Á¦¿¡ ´ëÇØ µå·°ÀÎÆ÷´Â 
                          Ã¥ÀÓÀ» ÁöÁö ¾Ê½À´Ï´Ù. ÀÚ¼¼ÇÑ ³»¿ëÀº ¡°Ã¥ÀÓÀÇ ÇÑ°è ¹× ¹ýÀû°íÁö¡±¸¦ ÂüÁ¶ÇØ ÁֽʽÿÀ.
                            ¹Ýµå½Ã Á¦Á¶¡¤¼öÀÔ»ç, ÆÇ¸Å»ç, ÀÇ»ç, ¾à»ç¿¡°Ô ÃÖÁ¾ÀûÀ¸·Î È®ÀÎÇϽñ⠹ٶø´Ï´Ù.
                          ÀüÈ: 02-3486-1061 ¤Ó À̸ÞÀÏ: webmaster@druginfo.co.kr
 | 
                    
                    | 
               
  
 
  
    ¾Æ·¡ÀÇ ³»¿ëÀ» Æ÷ÇÔÇÑ Àüü µ¥ÀÌÅ͸¦ º¸½Ã·Á¸é 
    ¿©±â·Î À̵¿ÇϽñ⠹ٶø´Ï´Ù.
   
  The database contains the following fields: The generic name of each chemical For module A10 (liver enzyme composite module): Overall activity category for each compound (A for active, M for marginally active, or I for inactive) based on the number of active and marginally active scores for each compound at the five individual endpoints (see research article for full description of method) Number of endpoints at which each compound is marginally active (M) Number of endpoints at which each compound is active (A) For modules A11 to A15 (alkaline phosphatase increased, SGOT increased, SGPT increased, LDH increased, and GGT increased, respectively): Overall activity category for each compound (A for active, M for marginally active, or I for inactive) based on the RI and ADR values (see the research article for full description of method) Number of ADR reports for each compound, given as <4 or ¡Ã4 Reporting Index value for each compound, except where no shipping units were available (NSU) Group 1 comprises of compounds for which ADR data were available for the first five years of marketing, so when no ADR reports were listed during this period the compounds were evaluated as inactive. Group 2 comprises of compounds for which a 'steady state' period of ADR data were available (1992-1996). In cases where no ADR reports were filed during this period, the compounds were scored as 'NA' (data not available) since they may have had one or more ADR reports during their first five years of marketing which should not be negated by a lack of ADR reports during the steady-state period. DEXAMETHASONE[GGT Increase][Composite Activity](Score)  NA(Marginal)  0(Active)  0[Alkaline Phosphatase Increase](Activity Score)  NA(Number of Rpts)  NA(Index value)  NA[SGOT Increase](Activity Score)  NA(Number of Rpts)  NA(Index value)  NA[SGPT Increase](Activity Score)  NA(Number of Rpts)  NA(Index value)  NA[LDH Increase](Activity Score)  NA(Number of Rpts)  NA(Index value)  NA[GGT Increase](Activity Score)  NA(Number of Rpts)  NA(Index value)  NA
 
  º´¿ë±Ý±â ¹× ƯÁ¤¿¬·É´ë ±Ý±â ¼ººÐ
 
  [ÀǾàǰº´¿ë/¿¬·É´ë±Ý±â °í½Ã±Ù°Å·Î ¹Ù·Î°¡±â]       Á¦¸ñ ¾øÀ½ 
 
    
    2008³â 8¿ù 1ÀÏ ¾à°¡ÈÀÏ»ó 8¿ù´Þ ½Å±ÔµîÀç ¹× »èÁ¦µÇ´Â ǰ¸ñ Æ÷ÇÔÇÑ º´¿ë¿¬·É ±Ý±â ǰ¸ñ¸®½ºÆ® ±âÁØ
    
    1. ÇöÀç °Ë»öÇÑ Á¦Ç°¿¡ ´ëÇÑ  º´¿ë±Ý±â Á¦Ç° Á¸Àç¿©ºÎ ¹× °Ë»ö
    ÇöÀç ÀÌÁ¦Ç°¿¡ ´ëÇÑ º´¿ë±Ý±â¿¡ ÇØ´çÇϴ û±¸Äڵ庰 Á¦Ç°³»¿ª °øÁö³»¿ëÀÌ ¾ø½À´Ï´Ù
          
    
    
    
    2. ¿¬·É´ë±Ý±â Á¸Àç¿©ºÎ
    ÇöÀç ÀÌÁ¦Ç°¿¡ ´ëÇÑ ¿¬·É±Ý±â¿¡ ÇØ´çÇϴ û±¸Äڵ庰 °øÁö³»¿ëÀÌ ¾ø½À´Ï´Ù
 
 
 
   
  |  
             
             | 
         
         
         | 
         |