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나리마신연고 [Bacitracin , Neomycin Sulfate , Polymyxin B Sulfate]
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일반의약품 | 삭제
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알림: |
드럭인포에서는 의약품 인터넷 판매를 하지 않습니다. |
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유료회원 결재시에는 보다 다양한 약물정보를
이용하실 수 있습니다.
유료정보목록은 전문회원으로
로그인 하시면 확인 가능합니다.
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 | 허가정보 |
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| 항목 |
내용 |
청구코드(KD코드)
비급여점검코드
상한금액 |
649603690[A05401661]
[보험코드에 따른 약품기본정보 직접조회]
\0 원/1g(2004.10.01)(현재약가)
[상병코드조회]
[질병코드조회]
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| 빠른조회 |
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| 허가사항 원문조회 |
[허가사항 원문조회]
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| 효능효과 |
[적응증 별 검색]
경미한[가벼운] 베인 상처, 긁힌 상처, 화상의 감염방지
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| 용법용량 |
* 절대 임의복용하지 마시고 반드시 의사 또는 약사와 상담하시기 바랍니다.
[처방약어]
상처부위를 깨끗이 하고 1일 1～3회 적당량을 상처부위에 바른다.
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| 주요약물 상호작용 |
[조회]
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| 금기 |
1) 이 약 성분에 과민증 및 그 병력이 있는 환자
2) 고막 천공[뚫림]이 있는 환자
3) 눈주위
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| 신중투여 |
1) 상처가 심하거나 화상이 심한 환자
2) 찔린 상처, 동물에 물린 상처
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| 이상반응 |
1) 과민증 : 발진 등의 증상이 나타날 수 있으므로 이러한 경우에는 사용을 중지하고 약사 또는 의사와 상의 합니다.
2) 장기 연용[계속 사용] : 신장애[신장장애], 난청[귀먹음]이 나타날 수 있으므로 장기연용[계속 사용]을 피합니다.
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| Related FDA Approved Drug |
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| 정보요약 |
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드럭인포 의약품 요약/상세정보
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| 코드 및 분류정보 |
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| 항목 |
내용 |
| 대표코드 |
8806496036903 |
| BIT 약효분류 |
감염증치료제 : 외용복합 (Anti-infectives /with steroids)
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| ATC 코드 |
Other antibiotics for topical use / D06AX
[코드분류상세설명]
[ATC코드예측]
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| 복지부분류코드 |
263 (화농성질환용제 )
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주성분코드 분석 및
중복처방 검토 |
[주성분코드 분석 및 중복처방 검토]
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| Drugs By Indication |
[전체보기]
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| Drugs By Classification |
[전체보기]
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| 제품정보 |
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| 항목 |
내용 |
청구코드(KD코드)
비급여점검코드
상한금액 |
649603690[A05401661]
[보험코드에 따른 약품기본정보 직접조회]
\0 원/1g(2004.10.01)(최신약가)
[상병코드조회]
[질병코드집 다운로드]
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| Brandname 정보 |
Polymyxin B Sulfate
Brand Names/Synonyms
- Aerosporin
- Poly-RX
- Polymixin B sulfate
- Polymyxin B sulfate salt
- Polymyxin B sulphate
Brand Name Mixtures
- Anaprime OPH Gel (Flumethasone + Neomycin sulfate + Polymyxin B sulfate)
- Antibiotic Cream (Gramicidin + Polymyxin B sulfate)
- Antibiotic Lozenges (Benzocaine + Cetylpyridinium Chloride + Polymyxin B sulfate + Tyrothricin)
- Antibiotic Ointment (Bacitracin + Polymyxin B sulfate)
- Bacitracin-Neomycin Polymyxin Ont (Bacitracin Zinc + Neomycin sulfate + Polymyxin B sulfate)
- Bacitracin-Neomycin-Polymyxin Oph Ont (Bacitracin Zinc + Neomycin sulfate + Polymyxin B sulfate)
- Band-Aid Brand Antibiotic (Bacitracin Zinc + Polymyxin B sulfate)
- Band-Aid-S-1 (Bacitracin Zinc + Polymyxin B sulfate)
- Cortisporin (Bacitracin Zinc + Hydrocortisone + Neomycin sulfate + Polymyxin B sulfate)
- First Aid Antibiotic (Bacitracin Zinc + Polymyxin B sulfate)
- First Aid Antibiotic Ointment (Bacitracin Zinc + Polymyxin B sulfate)
- Forte Topical Suspension (Hydrocortisone Acetate + Hydrocortisone Sodium Succinate + Neomycin sulfate + Penicillin G Procaine + Polymyxin B sulfate)
- Gercillin (Bacitracin + Benzocaine + Polymyxin B sulfate + Tyrothricin)
- Lanabiotic Ont (Bacitracin + Polymyxin B sulfate)
- Laryngets Loz (Benzocaine + Cetylpyridinium Chloride + Polymyxin B sulfate + Tyrothricin)
- Lidomyxin (Lidocaine Hydrochloride + Polymyxin B sulfate)
- Lidosporin Cream (Gramicidin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Lidosporin Ear Drops (Lidocaine Hydrochloride + Polymyxin B sulfate)
- Mastitis Care (Neomycin sulfate + Penicillin G Potassium + Polymyxin B sulfate + Streptomycin sulfate)
- Mycitracin OPH ONT (Bacitracin + Neomycin sulfate + Polymyxin B sulfate)
- Neo Bace Ophthalmic Ointment (Bacitracin + Polymyxin B sulfate)
- Neospan Mastitis Treatment (Neomycin sulfate + Penicillin G Potassium + Polymyxin B sulfate + Streptomycin sulfate)
- Neosporin Antibiotic Cream (Gramicidin + Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Eye-Ear Solution (Gramicidin + Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Irrigating Solution (Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Ointment (Bacitracin (Bacitracin Zinc) + Neomycin sulfate + Polymyxin B sulfate)
- Neosporin Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Neomycin sulfate + Polymyxin B sulfate)
- Neotopic Ointment (Bacitracin (Bacitracin Zinc) + Neomycin sulfate + Polymyxin B sulfate)
- Ophthocort Ont (Chloramphenicol + Hydrocortisone Acetate + Polymyxin B sulfate)
- Optiprime Oph Gel (Neomycin sulfate + Polymyxin B sulfate)
- Ozonol Antibiotic Plus - Ointment (Bacitracin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Ozonol Antibiotic Plus Ont (Bacitracin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Pms-Polytrimethoprim (Polymyxin B sulfate + Trimethoprim (Trimethoprim sulfate))
- Polycidin Eye, Ear Drops (Gramicidin + Polymyxin B sulfate)
- Polycidin Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Polymyxin B sulfate)
- Polyderm Antibiotic Ointment (Bacitracin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Polyderm Ointment Usp (Bacitracin Zinc + Polymyxin B sulfate)
- Polysporin Antibiotic Burn Cream (Gramicidin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Polysporin Antibiotic Ointment (Bacitracin + Polymyxin B sulfate)
- Polysporin Burn Formula Cream (Gramicidin + Lidocaine Hydrochloride + Polymyxin B sulfate)
- Polysporin Cream (Gramicidin + Polymyxin B sulfate)
- Polysporin Eye and Ear Drops Sterile (Gramicidin + Polymyxin B sulfate)
- Polysporin Sterile Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Polymyxin B sulfate)
- Polysporin Topical First Aid Antibiotic Ointment (Bacitracin + Polymyxin B sulfate)
- Polysporin Triple Antibiotic Ointment (Bacitracin + Gramicidin + Polymyxin B sulfate)
- Polytopic Ont (Bacitracin + Polymyxin B sulfate)
- Polytracin Ont (Bacitracin Zinc + Polymyxin B sulfate)
- Pulmosirum Pastille (Benzocaine + Cetylpyridinium Chloride + Polymyxin B sulfate + Tyrothricin)
- Sandoz Cortimyxin (Bacitracin (Bacitracin Zinc) + Hydrocortisone + Neomycin sulfate + Polymyxin B sulfate)
- Septomixine Forte (Dexamethasone + Halethazole Tartrate + Neomycin sulfate + Polymyxin B sulfate + Tyrothricin)
- Surolan Drops (Miconazole Nitrate + Polymyxin B sulfate + Prednisolone Acetate)
- Synalar Bi-Otic Solution (Fluocinolone Acetonide + Neomycin sulfate + Polymyxin B sulfate)
Chemical IUPAC NameN-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)
-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-
21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-6-methyl-octanamide;
sulfuric acidNeomycin Sulfate
Brand Names/Synonyms
- Biosol
- Bykomycin
- Caswell No. 595
- Endomixin
- Fradiomycin
- Fradiomycin Sulfate
- Fraquinol
- Lidamycin Creme
- Myacine
- Myacyne
- Mycifradin
- Mycifradin-N
- Myciguent
- Neo-Fradin
- Neo-Mantle Creme
- Neo-Rx
- Neobiotic
- Neobrettin
- Neofracin
- Neolate
- Neomix
- Neomycin B Sulfate
- Neomycin Sulfate
- Neomycin Sulphate
- Neomycin Sulphate Puriss for Bacteriology
- Neomycin trisulfate salt hydrate
- Neosulf
- Nivemycin
- Tuttomycin
- USAF CB-19
- Vonamycin Powder V
Brand Name Mixtures
- AK Spor liq (gramicidin + neomycin sulfate + polymyxin B sulfate)
- AK Trol Suspension (dexamethasone + neomycin sulfate + polymyxin B sulfate)
- Aminoderm Poudre (glycine + l-cysteine + neomycin sulfate + threonine)
- Anaprime oph gel (flumethasone + neomycin sulfate + polymyxin B sulfate)
- Bacitracin-neomycin polymyxin ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- Bacitracin-neomycin-polymixin ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- bacitracin-neomycin-polymyxin oph ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- beef cattle vit ade premix medicated (neomycin sulfate + oxytetracycline hydrochloride + vitamin A + vitamin D3 + vitamin e)
- Biosol-M-Aquadrops liq (methscopolamine bromide + neomycin sulfate)
- BNPH ont (bacitracin zinc + hydrocortisone acetate + neomycin sulfate + polymyxin B sulfate)
- Calf scour bolus (atropine sulfate + calcium phosphate + hyoscyamine sulfate + kaolin + neomycin sulfate + pectin + sulfaguanidine + sulfathiazole + vitamin A)
- Certreat Scours Oblets (chlortetracycline hydrochloride + neomycin sulfate + nicotinic acid + vitamin A + vitamin D)
- Cicatrin Powder (bacitracin zinc + glycine + l-cysteine + neomycin sulfate + threonine)
- Co-op pinkeye spray (gentian violet + neomycin sulfate)
- Cortisporin (bacitracin zinc + hydrocortisone + neomycin sulfate + polymyxin B sulfate)
- Derma-4 ont (neomycin sulfate + nystatin + thiostrepton (antibiotic of a streptomyces species) + triamcinolone acetonide)
- Dioptrol ointment (dexamethasone + neomycin sulfate + polymyxin B sulfate)
- dioptrol suspension (dexamethasone + neomycin sulfate + polymyxin B sulfate)
- Diosporin ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- Enterolyte (calcium chloride dihydrate + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine)
- FML-Neo oph sus (fluorometholone + neomycin sulfate)
- Forte topical suspension (hydrocortisone acetate + hydrocortisone sodium succinate + neomycin sulfate + penicillin g procaine + polymyxin B sulfate)
- Kaobiotic bolus (kaolin + neomycin sulfate + pectin + sulfadiazine + sulfaguanidine + sulfamerazine + sulfathiazole)
- Kaobiotic tab (kaolin + neomycin sulfate + pectin + sulfadiazine + sulfaguanidine + sulfamerazine + sulfathiazole)
- Kenacomb (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide)
- Keraplex spray (methyl violet + neomycin sulfate)
- Lidecomb cream (fluocinonide + gramicidin + neomycin sulfate + nystatin)
- Mastitis Care (neomycin sulfate + penicillin g potassium + polymyxin B sulfate + streptomycin sulfate)
- Maxitrol (dexamethasone + neomycin sulfate + polymyxin B sulfate)
- Mecomb Cream 0.1% (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide)
- Mycitracin oph ont (bacitracin + neomycin sulfate + polymyxin B sulfate)
- Neo Atropec 25 tab (aluminum hydroxide + atropine methylnitrate + kaolin + neomycin sulfate + pectin + sulfacetamide + sulfaguanidine)
- Neo Atropec C tab (aluminum hydroxide + atropine methylnitrate + kaolin + neomycin sulfate + pectin + sulfacetamide + sulfaguanidine)
- Neo Atropec tab (aluminum hydroxide + atropine methylnitrate + kaolin + neomycin sulfate + pectin + sulfacetamide + sulfaguanidine)
- Neo Chlor Powder (neomycin sulfate + tetracycline hydrochloride)
- Neo Darbazine Spansule Capsule no 1 (isopropamide iodide + neomycin sulfate + prochlorperazine maleate)
- Neo Darbazine Spansule no 3 (isopropamide iodide + neomycin sulfate + prochlorperazine maleate)
- Neo Oxymed Powder (neomycin sulfate + oxytetracycline hydrochloride)
- Neo P.P.G. (neomycin sulfate + penicillin g potassium)
- Neo Sulfa-E (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine)
- Neo Sulfalyte Bolus (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine)
- Neo Terramycin Soluble Powder (neomycin sulfate + oxytetracycline hydrochloride)
- neo-chlor (neomycin sulfate + tetracycline hydrochloride)
- Neo-Cortef (hydrocortisone acetate + neomycin sulfate)
- Neo-Medrol (methylprednisolone acetate + neomycin sulfate)
- Neo-Medrol Acne Lotion (aluminum chlorohydrate + methylprednisolone acetate + neomycin sulfate + sulfur)
- Neo-Oxytetracycline (neomycin sulfate + oxytetracycline hydrochloride)
- Neo-Terramycin 50/50 premix (neomycin sulfate + oxytetracycline hydrochloride)
- Neo-Tet pws (neomycin sulfate + oxytetracycline hydrochloride)
- Neodecadron Eye Ear Solution 0.1% (dexamethasone phosphate + neomycin sulfate)
- Neomix-Pamine Solution (methscopolamine bromide + neomycin sulfate)
- Neopaste (aluminum hydroxide + calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine + sulfathiazole)
- Neorease (neomycin sulfate + sulfamethazine + sulfathiazole)
- Neosol M Aquadrops (methscopolamine bromide + neomycin sulfate)
- Neospan Mastitis Treatment (neomycin sulfate + penicillin g potassium + polymyxin B sulfate + streptomycin sulfate)
- Neosporin antibiotic cream (gramicidin + neomycin sulfate + polymyxin B sulfate)
- Neosporin Eye-Ear Solution (gramicidin + neomycin sulfate + polymyxin B sulfate)
- Neosporin Irrigating Solution (neomycin sulfate + polymyxin B sulfate)
- Neosporin Ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- Neosporin Ophthalmic Ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- Neosulf (neomycin sulfate + sulfamethazine + sulfathiazole)
- Neosulf bolus (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine)
- Neosulf Plus bolus (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine)
- Neosulpec (kaolin + neomycin + pectin + sulfaguanidine + sulfamethazine + sulfathiazole)
- Neotet soluble concentrate (neomycin sulfate + oxytetracycline hydrochloride)
- Neotetramed Powder (neomycin sulfate + tetracycline hydrochloride)
- Neotopic ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- Neovast tabs (kaolin + neomycin sulfate + pectin + sulfadiazine + sulfaguanidine + sulfamerazine + sulfathiazole)
- Neox (neomycin sulfate + oxytetracycline hydrochloride)
- Ophtacin ophtalmic ointment (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- Ophtacin-H ophtalmic ointment (bacitracin zinc + hydrocortisone acetate + neomycin sulfate + polymyxin B sulfate)
- Optimyxin Plus Oto-opht GTTE (gramicidin + neomycin sulfate + polymyxin B sulfate)
- Optiprime oph gel (neomycin sulfate + polymyxin B sulfate)
- Optisone (neomycin + prednisolone)
- Oribiotic ointment (bacitracin + lidocaine + neomycin sulfate + nystatin + triamcinolone acetonide)
- Otizol HC liq (hydrocortisone acetate + lidocaine hydrochloride + neomycin sulfate)
- P.T. Booster (calcium d-pantothenate + neomycin sulfate + nicotinic acid + pyridoxine hydrochloride + streptomycin sulfate + vitamin A + vitamin B1 + vitamin B12 + vitamin B2 + vitamin D3)
- Panolog cream (neomycin sulfate + nystatin + thiostrepton [antibiotic of a streptomyces species] + triamcinolone acetonide)
- Panolog ointment (neomycin sulfate + nystatin + thiostrepton [antibiotic of a streptomyces species] + triamcinolone acetonide)
- Pinkeye Spray (gentian violet + neomycin sulfate)
- Previte (neomycin sulfate + selenium sulfide + streptomycin sulfate + vitamin A + vitamin D + vitamin e + vitamin K1)
- Proctosone ont (dibucaine hydrochloride + esculin + hydrocortisone acetate + neomycin sulfate)
- Proctosone sup (dibucaine hydrochloride + esculin + hydrocortisone acetate + neomycin sulfate)
- Ratio-Triacomb regular cream (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide)
- Sandoz Cortimyxin (bacitracin zinc + hydrocortisone + neomycin sulfate + polymyxin B sulfate)
- Scour bolus plus (calcium carbonate + magnesium oxide + menadione sodium bisulfite + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + streptomycin sulfate + sulfamerazine + sulfamethazine + sulfanilamide + sulfathiazole + vitamin A + vitamin D)
- Scour Solution (methscopolamine bromide + neomycin sulfate)
- Scour solution coop (methscopolamine bromide + neomycin sulfate)
- Scour suspension (atropine sulfate + calcium phosphate + hyoscyamine sulfate + kaolin + neomycin sulfate + pectin + succinylsulfathiazole)
- Scour treat liq (neomycin sulfate + sulfamethazine + sulfathiazole)
- Scour-plug (calcium chloride + magnesium chloride + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + sulfamethazine)
- Septomixine Forte (dexamethasone + halethazole tartrate + neomycin sulfate + polymyxin B sulfate + tyrothricin)
- Solvaderm ointment (neomycin sulfate + nystatin + thiostrepton [antibiotic of a streptomyces species] + triamcinolone acetonide)
- Spor-HC otic susp (hydrocortisone + neomycin sulfate + polymyxin B sulfate)
- Sulectim plus scour boluses (calcium carbonate + magnesium oxide + menadione sodium bisulfite + neomycin sulfate + potassium acetate + sodium acetate + sodium chloride + streptomycin sulfate + sulfamerazine + sulfamethazine + sulfanilamide + sulfathiazole sodium + vitamin A + vitamin D)
- Sulkamycin S Bolettes (neomycin sulfate + sulfamethazine)
- Synalar Bi-otic solution (fluocinolone acetonide + neomycin sulfate + polymyxin B sulfate)
- Theraderm cream (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide)
- Tresaderm dermatologic solution (dexamethasone + neomycin sulfate + thiabendazole)
- Triple sulfa plus neomycin (neomycin sulfate + sulfamerazine sodium + sulfamethazine sodium + sulfathiazole sodium)
- Vetropolycin HC ont (bacitracin zinc + hydrocortisone acetate + neomycin sulfate + polymyxin B)
- Vetropolycin ont (bacitracin zinc + neomycin sulfate + polymyxin B sulfate)
- Viaderm KC Cream (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide)
- Viaderm KC ont (gramicidin + neomycin sulfate + nystatin + triamcinolone acetonide)
- Wound & Pinkeye Spray (gentian violet + neomycin sulfate)
Chemical IUPAC Name(2S,3R,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3R,4R,5S)-5-[(1S,2R,3S,5R,6S)-3,5-
diamino-2-[(2R,3R,4R,5R,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxy-oxan-2-yl]oxy-6-
hydroxy-cyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy-oxane-3,4-diolBacitracin
Brand Names/Synonyms
- Baci-rx
- Baciguent
- Baciim
- Bacitracin Bacillus licheniformis
- Ziba-rx
Brand Name Mixtures
- Antibiotic Ointment (Bacitracin + Polymyxin B (Polymyxin B Sulfate))
- Aurex Rotenone Drops (Bacitracin + Penicillin + Rotenone + Streptomycin (Streptomycin Sulfate) + Undecylenic Acid)
- Baciguent Plus Pain Reliever Ont (Bacitracin + Lidocaine)
- Bacitracin-Neomycin Polymyxin Ont (Bacitracin Zinc + Neomycin Sulfate + Polymyxin B Sulfate)
- Bacitracin-Neomycin-Polymixin Ont (Bacitracin Zinc + Neomycin Sulfate + Polymyxin B Sulfate)
- Bacitracin-Neomycin-Polymyxin Oph Ont (Bacitracin Zinc + Neomycin Sulfate + Polymyxin B Sulfate)
- Band-Aid-S-1 (Bacitracin Zinc + Polymyxin B Sulfate)
- Cortisporin (Bacitracin (Bacitracin Zinc) + Hydrocortisone + Neomycin (Neomycin Sulfate) + Polymyxin B (Polymyxin B Sulfate))
- Cortisporin (Bacitracin Zinc + Hydrocortisone + Neomycin Sulfate + Polymyxin B Sulfate)
- Emercreme No4 Ont Efa (Bacitracin + Benzocaine + Cetylpyridinium Chloride + Diphenylpyraline Hydrochloride + Tyrothricin)
- First Aid Antibiotic (Bacitracin Zinc + Polymyxin B Sulfate)
- First Aid Antibiotic Ointment (Bacitracin Zinc + Polymyxin B Sulfate)
- Gercillin (Bacitracin + Benzocaine + Polymyxin B Sulfate + Tyrothricin)
- Lanabiotic Ont (Bacitracin + Polymyxin B Sulfate)
- Mycitracin Oph Ont (Bacitracin + Neomycin Sulfate + Polymyxin B Sulfate)
- Neo Bace Ophthalmic Ointment (Bacitracin + Polymyxin B Sulfate)
- Neosporin Ointment (Bacitracin (Bacitracin Zinc) + Neomycin (Neomycin Sulfate) + Polymyxin B (Polymyxin B Sulfate))
- Neosporin Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Neomycin (Neomycin Sulfate) + Polymyxin B (Polymyxin B Sulfate))
- Neotopic Ointment (Bacitracin (Bacitracin Zinc) + Neomycin (Neomycin Sulfate) + Polymyxin B (Polymyxin B Sulfate))
- Ozonol Antibiotic Plus - Ointment (Bacitracin + Lidocaine Hydrochloride + Polymyxin B (Polymyxin B Sulfate))
- Ozonol Antibiotic Plus Ont (Bacitracin + Lidocaine Hydrochloride + Polymyxin B Sulfate)
- Polycidin Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Polymyxin B (Polymyxin B Sulfate))
- Polyderm Antibiotic Ointment (Bacitracin + Lidocaine Hydrochloride + Polymyxin B Sulfate)
- Polysporin Antibiotic Ointment (Bacitracin + Polymyxin B (Polymyxin B Sulfate))
- Polysporin Sterile Ophthalmic Ointment (Bacitracin (Bacitracin Zinc) + Polymyxin B (Polymyxin B Sulfate))
- Polysporin Topical First Aid Antibiotic Ointment (Bacitracin + Polymyxin B (Polymyxin B Sulfate))
- Polysporin Triple Antibiotic Ointment (Bacitracin + Gramicidin + Polymyxin B (Polymyxin B Sulfate))
- Polytopic Ont (Bacitracin + Polymyxin B (Polymyxin B Sulfate))
- Polytracin Ont (Bacitracin Zinc + Polymyxin B (Polymyxin B Sulfate))
- Sandoz Cortimyxin (Bacitracin (Bacitracin Zinc) + Hydrocortisone + Neomycin (Neomycin Sulfate) + Polymyxin B (Polymyxin B Sulfate))
Chemical IUPAC Name4-[2-[[2-(1-amino-2-methyl-butyl)-4,5-dihydro-1,3-thiazol-5-yl]carbonylamino]-4-methyl-
pentanoyl]amino-5-[1-[[18-(3-aminopropyl)-12-benzyl-15-butan-2-yl-3-(carbamoylmethyl)
-6-(carboxymethyl)-9-(3H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,
13,16,19-heptazacyclopentacos-21-yl]carbamoyl]-2-methyl-butyl]amino-5-oxo-pentanoic
acid
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| 복약정보 |
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| 항목 |
내용 |
| LACTmed 바로가기 |
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| 약리작용 |
유료정보입니다.
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| 축약복약지도 |
유료정보입니다.
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| 복약지도 |
유료정보입니다.
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| 임부에대한투여 |
| * |
전체임신 기간별로 여러등급이 존재할 수 있으며 가장 위험도가 높은 정보만 보여집니다. 단, 복합제의 경우 모든 복합제성분에 대한 임부투여등급이 표시된것은 절대 아니며 표시된것중에 가장 위험도가 높은 정보만 나타납니다.
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FDA : C등급
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상기 임부투여에 대한 정보는 전산처리 되면서 입력 오류 가능성이 존재합니다. 오류 가능성을 최소화하기 위하여 많은 노력을 기울이고 있으나, 그 정확성에 대하여 확신을 드릴 수 없습니다. 이에 대해 회사는 책임을 지지 않습니다.
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신장애, 간장애시
용량조절 |
유료정보입니다.
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| Pharmacokinetics |
유료정보입니다.
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| 병용금기 및 연령대금기 근거조회 |
[병용금기 및 연령대금기 근거조회]
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| 제형별 복약지도 |
[연고] |
| 보관상 주의 |
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| 조제시 주의 |
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| 심사정보 |
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| 학술정보 |
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| 항목 |
내용 |
| DUR (의약품사용평가) |
병용금기 :
고시된 병용금기 내용은 없습니다.
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연령대금기 :
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[연령대금기상세검색]
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| 독성정보 |
Bacitracin에 대한 독성정보 : 정보보기
출처: 국립독성과학원 독성물질정보DB : http://www.nitr.go.kr/nitr/contents/m134200/view.do |
| Mechanism of Action |
Bacitracin에 대한 Mechanism_Of_Action 정보
Bacitracin intereferes with the dephosphorylation of the 55-carbon, biphosphate lipid transport molecule, which carries the building blocks of the peptidoglycan bacterial cell wall outside the inner membrane for construction.
Neomycin에 대한 Mechanism_Of_Action 정보
Aminoglycosides like neomycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.
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| Pharmacology |
Bacitracin에 대한 Pharmacology 정보
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. As a polypeptide, toxic, and difficult to use chemical, Bacitracin doesn't work well orally, however is very effective topically. Bacitracin exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy.
Neomycin에 대한 Pharmacology 정보
Neomycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
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| Metabolism |
Bacitracin에 대한 Metabolism 정보
# Phase_1_Metabolizing_Enzyme:Not Available
Neomycin에 대한 Metabolism 정보
# Phase_1_Metabolizing_Enzyme:Not Available
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| Protein Binding |
Bacitracin에 대한 단백결합 정보
Not Available
Neomycin에 대한 단백결합 정보
Protein binding studies have shown that the degree of aminoglycoside protein binding is low and, depending upon the methods used for testing, may be between 0% and 30%.
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| Half-life |
Bacitracin에 대한 반감기 정보
Not Available
Neomycin에 대한 반감기 정보
2 to 3 hours
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| Absorption |
Bacitracin에 대한 Absorption 정보
Absorption of bacitracin following intramuscular injection is rapid and complete. Absorption from the gastrointestinal tract following oral administration is not appreciable. Absorption following topical application is negligible.
Neomycin에 대한 Absorption 정보
Poorly absorbed from the normal gastrointestinal tract. Although only approximately 3% of neomycin is absorbed through intact intestinal mucosa, significant amounts may be absorbed through ulcerated or denuded mucosa or if inflammation is present.
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| Pharmacokinetics |
Bacitracin의 약물동력학자료
- 작용지속시간 : 6-8시간
- 흡수 :
- 외용 : 점막, 정상 피부, 손상된 피부로부터 거의 흡수되지 않는다.
- IM : 빠르게 흡수된다.
- 방광 관주 : 거의 흡수되지 않는다.
- 복막 세척, 종격동 세척 : 흡수된다.
- 분포 : 뇌수막염시에도 뇌척수액으로의 분포는 미미하다.
- 단백결합 : 혈중 단백에 거의 결합하지 않는다.
- 혈중최고농도 도달시간 : IM : 1-2시간
- 소실 : 24시간 이내에 10-40%가 천천히 신배설
Neomycin Sulfate의 약물동력학자료
- 흡수 : 경구, 경피 : 흡수되는 양이 미미하다. (3%)
- 분포 : 분포용적 : 0.36 L/kg
- 대사 : 소량이 간에서 대사된다.
- 반감기 : 3 시간 (나이와 신기능에 의존)
- 혈중최고농도 도달시간 :
- 경구 : 1-4 시간
- 근육주사 : 2 시간 이내
- 소실 :
- 주사제 : 신배설 (30-50%가 미변화체로 배설)
- 경구 : 97%가 미변화체로 변배설
Polymyxin B Sulfate의 약물동력학자료
- 흡수 :
- 복막에서 잘 흡수된다.
- 위장관(신생아 제외), 점막, 피부에서는 잘 흡수되지 않는다.
- 분포 :
- 반감기 : 4.5-6 시간, 신기능 저하시 연장된다.
- 혈중최고농도 도달시간 : IM : 2시간 이내
- 소실 : 사구체 여과를 통해 60% 이상이 미변화체로 신배설된다.
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| Biotransformation |
Bacitracin에 대한 Biotransformation 정보
Not Available
Neomycin에 대한 Biotransformation 정보
Neomycin undergoes negligible biotransformation after parenteral administration.
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| Toxicity |
Bacitracin에 대한 Toxicity 정보
Oral, mouse: LD50 = >3750 mg/kg.
Neomycin에 대한 Toxicity 정보
LD50 = 200 mg/kg (rat). Because of low absorption, it is unlikely that acute overdosage would occur with oral neomycin. However, prolonged administration could result in sufficient systemic drug levels to produce neurotoxicity, ototoxicity and/or nephrotoxicity.
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| Drug Interactions |
Bacitracin에 대한 Drug_Interactions 정보
Not Available
Neomycin에 대한 Drug_Interactions 정보
Not Available
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CYP450
Drug Interaction |
[CYP450 Table직접조회]
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| Food Interaction |
Bacitracin에 대한 Food Interaction 정보
Not Available
Neomycin에 대한 Food Interaction 정보
Not Available
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| Drug Target |
[Drug Target]
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| Description |
Bacitracin에 대한 Description 정보
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically.Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), which means that ribosomes are not involved in its synthesis.
Neomycin에 대한 Description 정보
A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)
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| Dosage Form |
Bacitracin에 대한 Dosage_Form 정보
Ointment TopicalPowder, for solution Intramuscular
Neomycin에 대한 Dosage_Form 정보
Dressing TopicalOintment OphthalmicSolution / drops Ophthalmic
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| Drug Category |
Bacitracin에 대한 Drug_Category 정보
Anti-Bacterial AgentsAnti-Infective Agents, Local
Neomycin에 대한 Drug_Category 정보
Anti-Bacterial AgentsAntibiotics
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| Smiles String Canonical |
Bacitracin에 대한 Smiles_String_canonical 정보
CCC(C)C(N)C1=NCC(S1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(C(C)CC)C(=O)NC1CCCCNC(=O)C(CC(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(CC2=CN=CN2)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(NC(=O)C(CCCN)NC1=O)C(C)CC
Neomycin에 대한 Smiles_String_canonical 정보
NCC1OC(OC2C(N)CC(N)C(O)C2OC2OC(CO)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O
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| Smiles String Isomeric |
Bacitracin에 대한 Smiles_String_isomeric 정보
CC[C@@H](C)[C@H](N)C1=NC[C@@H](S1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC1=O)[C@H](C)CC
Neomycin에 대한 Smiles_String_isomeric 정보
NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
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| InChI Identifier |
Bacitracin에 대한 InChI_Identifier 정보
InChI=1/C66H103N17O16S/c1-9-35(6)52(69)66-72-32-48(100-66)63(97)80-43(26-34(4)5)59(93)75-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)76-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-73-39)77-60(94)44(27-38-18-13-12-14-19-38)81-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)74-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,73)(H,71,89)(H,74,90)(H,75,93)(H,76,98)(H,77,94)(H,78,96)(H,79,95)(H,80,97)(H,81,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36?,37?,40-,41+,42+,43-,44+,45-,46-,47+,48?,52-,53-,54-/m0/s1/f/h71,73-83,85,87H,68H2
Neomycin에 대한 InChI_Identifier 정보
InChI=1/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
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| Chemical IUPAC Name |
Bacitracin에 대한 Chemical_IUPAC_Name 정보
(4R)-4-[[(2S)-2-[[2-[(1S)-1-amino-2-methylbutyl]4,5-dihydro-1,3-thiazole-5-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-15-butan-2-yl-6-(carboxymethyl)-9-(3H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-12-(phenylmethyl)-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Neomycin에 대한 Chemical_IUPAC_Name 정보
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
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| Drug-Induced Toxicity Related Proteins |
NEOMYCIN 의 Drug-Induced Toxicity Related Protein정보
Replated Protein:NMDA receptor-regulated protein
Drug:neomycin
Toxicity:excitotoxic activation.
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