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키드골드츄어블정 KID GOLD CHEWABLE TAB.[Ascorbic Acid , Calcium pantothenate , Cholecalciferol dried , Cyanocobalamin , Dibasic calcium phosphate
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일반의약품 | 비급여
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알림: |
드럭인포에서는 의약품 인터넷 판매를 하지 않습니다. |
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유료회원 결재시에는 보다 다양한 약물정보를
이용하실 수 있습니다.
유료정보목록은 전문회원으로
로그인 하시면 확인 가능합니다.
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 | 허가정보 |
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| 항목 |
내용 |
청구코드(KD코드)
비급여점검코드
상한금액 |
비급여
[상병코드조회]
[질병코드조회]
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| 빠른조회 |
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| 제품성상 |
적색의 딸기향이 있는 원형의 씹어먹는 정제 [제형정보 확인] |
| 포장·유통단위 |
120T |
| 효능효과 |
[적응증 별 검색]
- 다음 경우의 비타민 A, D, E, B1, B2, B6, C의 보급: 육체피로, 임신·수유기, 병중·병후의 체력저하시, 발육기, 노년기
- 눈의 건조감의 완화
- 야맹증
- 뼈, 이의 발육불량
- 구루병의 예방
- 칼슘결핍 및 기타 칼슘의 보급
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| 용법용량 |
* 절대 임의복용하지 마시고 반드시 의사 또는 약사와 상담하시기 바랍니다.
[처방약어]
3세 - 12세 미만 : 1회 1정, 1일 2회
12세 이상 및 성인 : 1회 2정, 1일 2회
입안에서 녹이거나 씹어서 복용한다.
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| 금기 |
- 과칼슘혈증(hypercalciumia :
혈액중에 칼슘이 과잉으로 존재하는 상태)환자, 유육정용, 신질환 환자
이 약 및 이 약에 포함된 성분에 과민증이 있는 환자
12개월 미만의 영아
신결석 환자
중증의 신부전 환자 |
| 이상반응 |
- 이 약 투여에 의하여 구역, 발진, 구토, 가려움증, 건조하고 거친 피부, 통증성 관절부종, 설사, 위부불쾌감, 변비, 발적, 묽은 변, 식욕부진, 복부팽만감, 저혈압, 얼굴 달아오름, 심박동불규칙의 증상이 있을 경우에는 복용을 중지하고 의사 또는 약사와 상의한다.
- 이 약의 투여에 의하여 생리가 예정보다 빨라지거나 양이 점점 많아 질 수 있으며, 출혈이 오래 지속될 수도 있다.
- 피리독신을 1일 500mg~2g의 용량으로 장기간 복용하면 감각신경병 또는 신경병적 증상(neuropathy :
말초신경계의 기능적 장애 또는 병적변화)이 나타날 수 있다.
- 엽산이 부족한 환자에게 비타민 B12를 1일 10㎍ 이상 투여할 경우 혈액학적 반응이 나타날 수 있다.
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| 상호작용 |
- 항알도스테론제, 트리암테렌과 병용투여시 고칼륨혈증을 일으킬 수 있으므로 주의한다.
- 이 약을 투여할 경우에는 다음의 약물과 병용투여하지 않는다.
- 녹차, 홍차 등 탄닌을 함유하는 차는 복용중, 복용전후에는 피한다.
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| Off-label Usage |
[조회]
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| Related FDA Approved Drug |
기준 성분: DIBASICAMINOSYN 7% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN 8.5% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 10% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 3.5% M (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; SODIUM CHLORIDE; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE)
AMINOSYN II 3.5% M IN DEXTROSE 5% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; SODIUM CHLORIDE; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE)
AMINOSYN II 3.5% M IN PLASTIC CONTAINER (AMINO ACIDS; MAGNESIUM ACETATE; POTASSIUM ACETATE; SODIUM CHLORIDE; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE)
AMINOSYN II 3.5% W/ ELECTROLYTES IN DEXTROSE 25% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 3.5% W/ ELECTROLYTES IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 4.25% M IN DEXTROSE 10% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; SODIUM CHLORIDE; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE)
AMINOSYN II 4.25% W/ ELECT AND ADJUSTED PHOSPHATE IN DEXTROSE 10% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM ACETATE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 4.25% W/ ELECTROLYTES IN DEXTROSE 20% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 4.25% W/ ELECTROLYTES IN DEXTROSE 25% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 4.25% W/ ELECTROLYTES IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 5% W/ ELECTROLYTES IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 7% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
AMINOSYN II 8.5% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE)
CLINIMIX E 2.75/10 SULFITE-FREE W/ ELECT IN DEXTROSE 10% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 2.75/25 SULFITE-FREE W/ ELECT IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 2.75/5 SULFITE-FREE W/ ELECT IN DEXTROSE 5% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 4.25/10 SULFITE-FREE W/ ELECT IN DEXTROSE 10% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 4.25/20 SULFITE-FREE W/ ELECT IN DEXTROSE 20% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 4.25/25 SULFITE-FREE W/ ELECT IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 4.25/5 SULFITE-FREE W/ ELECT IN DEXTROSE 5% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 5/10 SULFITE-FREE W/ ELECT IN DEXTROSE 10% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 5/15 SULFITE-FREE W/ ELECT IN DEXTROSE 15% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 5/20 SULFITE-FREE W/ ELECT IN 20% DEXTROSE W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 5/25 SULFITE-FREE W/ ELECT IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
CLINIMIX E 5/35 SULFITE-FREE W/ ELECT IN DEXTROSE 35% W/ CALCIUM IN PLASTIC CONTAINER (AMINO ACIDS; CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
ELLIOTTS B SOLUTION (CALCIUM CHLORIDE; DEXTROSE; MAGNESIUM SULFATE; POTASSIUM CHLORIDE; SODIUM BICARBONATE; SODIUM CHLORIDE; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE)
IONOSOL B AND DEXTROSE 5% IN PLASTIC CONTAINER (DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM CHLORIDE; SODIUM LACTATE; SODIUM PHOSPHATE, MONOBASIC ANHYDROUS)
ISOLYTE M IN DEXTROSE 5% IN PLASTIC CONTAINER (DEXTROSE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
ISOLYTE M W/ DEXTROSE 5% IN PLASTIC CONTAINER (DEXTROSE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
ISOLYTE P IN DEXTROSE 5% IN PLASTIC CONTAINER (DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE)
ISOLYTE P W/ DEXTROSE 5% IN PLASTIC CONTAINER (DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE)
ISOLYTE S PH 7.4 IN PLASTIC CONTAINER (MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; POTASSIUM PHOSPHATE, MONOBASIC; SODIUM ACETATE; SODIUM CHLORIDE; SODIUM GLUCONATE; SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE)
OSMOPREP (SODIUM PHOSPHATE, DIBASIC ANHYDROUS; SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE)
SODIUM PHOSPHATES IN PLASTIC CONTAINER (SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE; SODIUM PHOSPHATE, MONOBASIC ANHYDROUS)
TRAVASOL 2.75% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 10% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 2.75% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 15% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 2.75% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 20% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 2.75% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 25% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 2.75% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 5% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 3.5% SULFITE FREE W/ ELECTROLYTES IN PLASTIC CONTAINER (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 3.5% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 4.25% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 10% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 4.25% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 15% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 4.25% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 20% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 4.25% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 25% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 4.25% SULFITE FREE W/ ELECTROLYTES IN DEXTROSE 5% IN PLASTIC CONTAINER (AMINO ACIDS; DEXTROSE; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 5.5% SULFITE FREE W/ ELECTROLYTES IN PLASTIC CONTAINER (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 5.5% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 8.5% SULFITE FREE W/ ELECTROLYTES IN PLASTIC CONTAINER (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
TRAVASOL 8.5% W/ ELECTROLYTES (AMINO ACIDS; MAGNESIUM CHLORIDE; POTASSIUM PHOSPHATE, DIBASIC; SODIUM ACETATE; SODIUM CHLORIDE)
VISICOL (SODIUM PHOSPHATE, DIBASIC ANHYDROUS; SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE)
기준 성분: CYANOCOBALAMINBEROCCA PN (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A PALMITATE; VITAMIN E)
BERUBIGEN (CYANOCOBALAMIN)
BETALIN 12 (CYANOCOBALAMIN)
CALOMIST (CYANOCOBALAMIN)
CERNEVIT-12 (ALPHA-TOCOPHEROL; ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; FOLIC ACID; NIACINAMIDE; PANTOTHENIC ACID; PYRIDOXINE; RIBOFLAVIN; THIAMINE; VITAMIN A)
COBAVITE (CYANOCOBALAMIN)
CYANOCOBALAMIN (CYANOCOBALAMIN)
CYANOCOBALAMIN CO 57 SCHILLING TEST KIT (CYANOCOBALAMIN; CYANOCOBALAMIN, CO-57; INTRINSIC FACTOR)
DEPINAR (CYANOCOBALAMIN; TANNIC ACID; ZINC ACETATE)
DICOPAC KIT (CYANOCOBALAMIN; CYANOCOBALAMIN, CO-57; CYANOCOBALAMIN, CO-58)
INFUVITE ADULT (ALPHA-TOCOPHEROL ACETATE; ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A PALMITATE; VITAMIN K)
INFUVITE PEDIATRIC (ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K)
INFUVITE PEDIATRIC (PHARMACY BULK PACKAGE) (ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K)
M.V.C. 9+3 (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I. ADULT (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E; VITAMIN K)
M.V.I. ADULT (PHARMACY BULK PACKAGE) (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E; VITAMIN K)
M.V.I. PEDIATRIC (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I.-12 (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I.-12 (WITHOUT VITAMIN K) (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I.-12 LYOPHILIZED (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE; VITAMIN A; VITAMIN E)
MVC PLUS (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
NASCOBAL (CYANOCOBALAMIN)
REDISOL (CYANOCOBALAMIN)
RUBIVITE (CYANOCOBALAMIN)
RUBRAMIN PC (CYANOCOBALAMIN)
RUBRATOPE-57 (CYANOCOBALAMIN, CO-57)
RUBRATOPE-57 KIT (COBALT CHLORIDE, CO-57; CYANOCOBALAMIN; CYANOCOBALAMIN, CO-57; INTRINSIC FACTOR)
RUBRATOPE-60 (CYANOCOBALAMIN, CO-60)
RUBRATOPE-60 KIT (COBALT CHLORIDE, CO-60; CYANOCOBALAMIN; CYANOCOBALAMIN, CO-60; INTRINSIC FACTOR)
RUVITE (CYANOCOBALAMIN)
VIBISONE (CYANOCOBALAMIN)
VITAPED (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PANTOTHENIC ACID; PHYTONADIONE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; VITAMIN A PALMITATE; VITAMIN E)
VI-TWEL (CYANOCOBALAMIN)
기준 성분: CHOLECALCIFEROL DRIED기준 성분: CALCIUM PANTOTHENATE기준 성분: ASCORBIC ACIDMOVIPREP (ASCORBIC ACID; POLYETHYLENE GLYCOL 3350; POTASSIUM CHLORIDE; SODIUM ASCORBATE; SODIUM CHLORIDE; SODIUM SULFATE)
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| 정보요약 |
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드럭인포 의약품 요약/상세정보
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| 코드 및 분류정보 |
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| 항목 |
내용 |
| BIT 약효분류 |
기타 비타민/영양제류 (Other Vitamins & Nutritional Supplements)
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| ATC 코드 |
Multivitamins and calcium / A11AA02
[코드분류상세설명]
[ATC코드예측]
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| 복지부분류코드 |
316 (혼합비타민제(비타민AD혼합제제를 제외) )
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| Drugs By Indication |
[전체보기]
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| Drugs By Classification |
[전체보기]
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| 제품정보 |
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| 복약정보 |
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| 항목 |
내용 |
| LACTmed 바로가기 |
[바로가기]
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| 약리작용 |
유료정보입니다.
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| 복약지도 |
유료정보입니다.
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| 임부에대한투여 |
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전체임신 기간별로 여러등급이 존재할 수 있으며 가장 위험도가 높은 정보만 보여집니다. 단, 복합제의 경우 모든 복합제성분에 대한 임부투여등급이 표시된것은 절대 아니며 표시된것중에 가장 위험도가 높은 정보만 나타납니다.
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FDA : A등급
(ascorbic acid;cyanocobalamin;folic acid;pyridoxine; )
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상기 임부투여에 대한 정보는 전산처리 되면서 입력 오류 가능성이 존재합니다. 오류 가능성을 최소화하기 위하여 많은 노력을 기울이고 있으나, 그 정확성에 대하여 확신을 드릴 수 없습니다. 이에 대해 회사는 책임을 지지 않습니다.
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반드시 공신력 있는 문헌을 다시 한번 참고 하시기 바라며 의사 또는 약사의 판단에 따라 투여여부가 결정되어야 합니다.
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| Pharmacokinetics |
유료정보입니다.
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| 병용금기 및 연령대금기 근거조회 |
[병용금기 및 연령대금기 근거조회]
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| 복약라벨 |
| 이미지 |
복약설명 |
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변비가 생길수 있습니다. |
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복약이미지는 모든 복약지도 사항을 표시한것은 아니며, 추가적으로 업데이트되거나 수정될 수 있습니다. |
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복약이미지의 표시여부는 실제 약물복용시 중요도에 따른것은 아니며 단순히 허가정보상 키워드를 기준으로 등록되었습니다. |
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귀하가 복약이미지 정보를 신뢰함은 전적으로 귀하의 책임입니다. 드럭인포는 이에 대한 어떠한 보증도 하지 않습니다. |
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| 보관상 주의 |
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| 조제시 주의 |
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| 심사정보 |
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| 학술정보 |
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| 항목 |
내용 |
| DUR (의약품사용평가) |
병용금기 :
고시된 병용금기 내용은 없습니다.
[상호작용/병용금기검색]
연령대금기 :
고시된 연령금기 내용은 없습니다.
[연령대금기상세검색]
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| 독성정보 |
Ascorbic Acid에 대한 독성정보 : 정보보기
Calcium에 대한 독성정보 : 정보보기
Cyanocobalamin에 대한 독성정보 : 정보보기
Folic acid에 대한 독성정보 : 정보보기
Nicotinamide에 대한 독성정보 : 정보보기
Pyridoxine에 대한 독성정보 : 정보보기
출처: 국립독성과학원 독성물질정보DB : http://www.nitr.go.kr/nitr/contents/m134200/view.do |
| Mechanism of Action |
Calcium에 대한 Mechanism_Of_Action 정보
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human proteins are known to bind or transport calcium. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Parathyroid hormone (secreted from the parathyroid gland) regulates the resorption of Ca2+ from bone. Calcitonin stimulates incorporation of calcium in bone, although this process is largely independent of calcitonin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast. The currently recommended calcium intake is 1,500 milligrams per day for women not taking estrogen and 800 milligrams per day for women on estrogen. There is close to 300 milligrams of calcium in one cup of fluid milk. Calcium carbonate is currently the best and least expensive form of calcium supplement available.
Cholecalciferol에 대한 Mechanism_Of_Action 정보
The first step involved in the activation of vitamin D3 is a 25-hydroxylation which is catalysed by the 25-hydroxylase in the liver and then by other enzymes. The mitochondrial sterol 27-hydroxylase catalyses the first reaction in the oxidation of the side chain of sterol intermediates. The active form of vitamin D3 (calcitriol) binds to intracellular receptors that then function as transcription factors to modulate gene expression. Like the receptors for other steroid hormones and thyroid hormones, the vitamin D receptor has hormone-binding and DNA-binding domains. The vitamin D receptor forms a complex with another intracellular receptor, the retinoid-X receptor, and that heterodimer is what binds to DNA. In most cases studied, the effect is to activate transcription, but situations are also known in which vitamin D suppresses transcription. Calcitriol increases the serum calcium concentrations by: increasing GI absorption of phosphorus and calcium, increasing osteoclastic resorption, and increasing distal renal tubular reabsorption of calcium. Calcitriol appears to promote intestinal absorption of calcium through binding to the vitamin D receptor in the mucosal cytoplasm of the intestine. Subsequently, calcium is absorbed through formation of a calcium-binding protein.
Cyanocobalamin에 대한 Mechanism_Of_Action 정보
Vitamin B12 is used in the body in two forms: Methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells.
calcium에 대한 Mechanism_Of_Action 정보
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human proteins are known to bind or transport calcium. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Parathyroid hormone (secreted from the parathyroid gland) regulates the resorption of Ca2+ from bone. Calcitonin stimulates incorporation of calcium in bone, although this process is largely independent of calcitonin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast. The currently recommended calcium intake is 1,500 milligrams per day for women not taking estrogen and 800 milligrams per day for women on estrogen. There is close to 300 milligrams of calcium in one cup of fluid milk. Calcium carbonate is currently the best and least expensive form of calcium supplement available.
Pyridoxine에 대한 Mechanism_Of_Action 정보
Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP). Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin B6, principally in the form of the coenzyme pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).
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| Pharmacology |
Cholecalciferol에 대한 Pharmacology 정보
Cholecalciferol (vitamin D3) is a steroid hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, in mineralization of bone, and for the assimilation of Vitamin A. The classical manifestations of vitamin D deficiency is rickets, which is seen in children and results in bony deformaties including bowed long bones. Deficiency in adults leads to the disease osteomalacia. Both rickets and osteomalacia reflect impaired mineralization of newly synthesized bone matrix, and usually result from a combination of inadequate exposure to sunlight and decreased dietary intake of vitamin D. Common causes of vitamin D deficiency include genetic defects in the vitamin D receptor, severe liver or kidney disease, and insufficient exposure to sunlight. Vitamin D plays an important role in maintaining calcium balance and in the regulation of parathyroid hormone (PTH). It promotes renal reabsorption of calcium, increases intestinal absorption of calcium and phosphorus, and increases calcium and phosphorus mobilization from bone to plasma.
Cyanocobalamin에 대한 Pharmacology 정보
Cyanocobalamin (Vitamin B12) is a water-soluble organometallic compound with a trivalent cobalt ion bound inside a corrin ring. It is needed for nerve cells and red blood cells, and to make DNA. Vitamin B12 deficiency is the cause of several forms of anemia.
Pyridoxine에 대한 Pharmacology 정보
Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.
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| Metabolism |
Cholecalciferol에 대한 Metabolism 정보
# Phase_1_Metabolizing_Enzyme:Cytochrome P450 24A1 (CYP24A1)Cytochrome P450 11A1 (CYP11A1)
Cyanocobalamin에 대한 Metabolism 정보
# Phase_1_Metabolizing_Enzyme:Methylenetetrahydrofolate reductase
Pyridoxine에 대한 Metabolism 정보
# Phase_1_Metabolizing_Enzyme:Methylenetetrahydrofolate reductase
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| Protein Binding |
Cholecalciferol에 대한 단백결합 정보
50% to 80%
Cyanocobalamin에 대한 단백결합 정보
Very high (to specific plasma proteins called transcobalamins); binding of hydroxocobalamin is slightly higher than cyanocobalamin.
Pyridoxine에 대한 단백결합 정보
22%
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| Half-life |
Cholecalciferol에 대한 반감기 정보
Several weeks
Cyanocobalamin에 대한 반감기 정보
Approximately 6 days (400 days in the liver).
Pyridoxine에 대한 반감기 정보
15-20 days
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| Absorption |
Cholecalciferol에 대한 Absorption 정보
Readily absorbed
Cyanocobalamin에 대한 Absorption 정보
Readily absorbed in the lower half of the ileum.
Pyridoxine에 대한 Absorption 정보
The B vitamins are readily absorbed from the gastrointestinal tract, except in malabsorption syndromes. Pyridoxine is absorbed mainly in the jejunum.
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| Pharmacokinetics |
Thiamine nitrate rocoat의 약물동력학자료
- 흡수 :
- 경구 : 최대흡수량 : 8-15 mg/day
- 근육주사 : 신속하고 완전하게 흡수된다.
- 분포 : 최소요구량 (약 1 mg/day)을 초과 섭취시 조직 저장에 포화가 나타난다.
- 소실 : 과잉 섭취된 양은 뇨를 통해 배설된다.
Nicotinamide rocoat의 약물동력학자료
- 작용발현시간 : pellagra : 24시간
- 흡수 : 위장관으로부터 신속하게 흡수된다.
- 분포 :
- 모든 조직으로 신속하게 분포한다.
- 태아 및 신생아에서의 농도가 모체의 농도보다 높다.
- 대사 : 간대사
- Nicotinamide는 생체 내에서 niacin의 대사로부터 형성될 수 있다.
- Dietrich pathway를 통해 효소적으로 NAD 및 NADP로 전환된다.
- 반감기 : 45분
- 혈중최고농도 도달시간 : 20-70분
- 소실 : 용량의존적으로 미변화체 및 대사체로서 신배설된다. (생리적 용량에서는 소량만이 미변화체로 신배설되나 고용량 투여시 주로 미변화체로 신배설된다.)
Folic Acid의 약물동력학자료
- 최고효과 발현시간 : 0.5-1시간 내로 나타난다.
- 흡수 : 소장의 근위부분(proximal part)에서 이루어진다.
Dl-tocopherol acetate 50%의 약물동력학자료
- 흡수 : 경구 :
- 소장으로부터 흡수되는 데에는 담즙이 필요하다.
- 흡수 저하 : 흡수장애 환자, 저체중 미숙아, 고용량 투여
- 유화제제보다 수용성 제제가 더 잘 흡수된다.
- 분포 : 모든 조직에 분포하며, 특히 지방조직에 고농도로 분포하고 저장된다.
- 대사 : 간에서 glucuronides 포합
- 소실 : 주로 담즙을 통해 (70-80%) 배설된다.
Cholecalciferol dried의 약물동력학자료
- 흡수 : 위장관으로부터 잘 흡수된다.
- 분포 : 흡수 후 chylomicrons을 통해 혈중으로 수송되며, 주로 간에 저장되고 기타 지방, 근육, 피부 및 골 조직 등에도 존재한다.
- 단백결합 : 주로 vitamin D-binding α-globulin에 결합하며 albumin과도 결합한다.
- 대사 : 간에서 vitamin D 25-hydroxylase에 의해 25-[OH] D로 대사된 후, 신장에서 vitamin D 1-hydroxylase에 의해 활성형인 1,25-[OH]2 D로 대사된다.
- 반감기 : vitamin D : 혈장 내에서 19-25 시간
- 소실 : 주로 담즙 및 대변을 통해 배설되며 소량은 뇨를 통해 배설된다.
Ascorbic Acid의 약물동력학자료
- 흡수 :
- 소장에서 거의 완전히 흡수된다.
- 흡수는 능동수송을 통해 이루어지며 용량의존적이라 여겨진다. (고용량에서 흡수 포화)
- 분포 : 널리 분포
- 단백결합 : 약 25%
- 대사 : 간에서 산화 및 황산 포합 등으로 대사된다.
- 반감기 : 16일
- 혈중최고농도 도달시간 : 정상 성인 : 2-3 시간
- 소실 :
- 주 배설 경로는 신장 및 담즙이다.
- 신배설은 용량의존적으로, 투여량이 증가하면 신배설량 및 속도가 증가한다.
Retinol palmitate dried의 약물동력학자료
- 흡수 :
- Retinol은 소장에서 흡수되며 retinoic acid는 문맥을 통해 전신적으로 흡수된다.
- 생리적 보충량의 용량 이하에서는 잘 흡수된다.
- 유화 제제보다 수용성 제제가 보다 신속하게 흡수된다.
- 고용량, 지질 흡수장애, 저단백식이, 간질환, 췌장 질환에서는 흡수가 저하된다.
- 림프의 chylomicrons에 의해 간으로 수송된다.
- 분포 :
- 간에 고농도로 저장된다. (약 2년 동안의 요구량이 간에 저장됨)
- 유즙 분비
- RBP (retinol-binding protein)에 결합된 retinol의 형태로 간으로부터 운반된다.
- 대사 : glucuronide 포합, 장간순환
- 소실 : 담즙을 통해 대변으로 배설된다.
Dibasic calcium phosphate의 약물동력학자료
- 흡수 : 위장관을 통해 이온화 형태로 흡수되며 비타민 D가 필요 ; 산성에서 흡수증가
- 생체내이용률 : 4-45 % ; 제제마다 다르다.
- 음식물의 영향 : 칼슘흡수(10-30 %)증가
섬유소가 많은 음식은 위장관 배출시간을 지체시켜 칼슘흡수를 저하시킴
- 분포 : 태반통과; 유즙분비
- 단백결합 : 45 %
- 소실 : 흡수되지 않은 칼슘은 주로 변으로 배설
신배설 : 20 % (50-300 mg/day)
Pyridoxine hydrochloride rocoat의 약물동력학자료
- 흡수 : 위장관으로부터 잘 흡수된다.
- 대사 : 간에서 4-pyridoxic acid로 대사된다.
- 반감기 : 15-20일
- 혈중최고농도 도달시간 : 경구 : 1.25 시간
- 소실 : 4-pyridoxic acid로 신배설되며, 소량 (약 2%)은 담즙을 통해 배설된다.
Calcium pantothenate의 약물동력학자료
- 흡수 : 경구 : 잘 흡수된다.
- 소실 : 약 70%는 미변화체로 소변을 통해, 약 30%는 대변을 통해 배설된다.
Cyanocobalamin의 약물동력학자료
- 흡수 :
- 경구 투여시 소장 원위부로부터 불규칙적으로 흡수된다.
- 능동 흡수에는 IF와의 복합체 형성이 필수적이며, 장관벽을 통해 수동 흡수도 가능하다.
- 위, 회장에 구조적 손상이나 기능적 손상이 있는 경우 흡수가 감소한다.
- 분포 :
- 위에서 위점막에 의해 분비되는 당단백인 IF (intrinsic factor)에 결합한다.
- 장관 점막세포 내에서 vitamin B12-IF 복합체로부터 vitamin B12가 유리된 후, 혈액 내에서 주로 특이적인 β-globulin 수송단백질인 transcobalamin II와 결합한다.
- 간, 골수 및 태반을 포함한 기타 조직으로 분포하며, 주로 간 (50-90%)에 저장된다.
- 단백결합 : 주로 transcobalamin II와 결합하며, 소량은 transcobalamin I (α-glycoprotein의 일종) 및 transcobalamin III (inter-α-glycoprotein의 일종)과 결합한다.
- 대사 : 장간순환
- 소실 :
- Vitamin B12를 투여받고 있지 않는 정상인 : 많은 양이 담즙 배설 후 장간순환한다.
- 일일 turnover rate : 체내 총저장량의 0.05-0.2% (범위 : 0.4-8 μg)
- 일일 신배설량은 대개 0.25 μg 이하
- Vitamin B12를 투여받는 경우 : 0.1-1 mg 근육주사 또는 정맥주사 후 48시간 이내에 50-90%가 신배설된다.
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| Biotransformation |
Cholecalciferol에 대한 Biotransformation 정보
Within the liver, cholecalciferal is hydroxylated to calcidiol (25-hydroxycholecalciferol) by the enzyme 25-hydroxylase. Within the kidney, calcidiol serves as a substrate for 1-alpha-hydroxylase, yielding calcitriol (1,25-dihydroxycholecalciferol), the biologically active form of vitamin D3.
Cyanocobalamin에 대한 Biotransformation 정보
Hepatic
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| Toxicity |
Cholecalciferol에 대한 Toxicity 정보
Hypercalcemia - Early symptoms of hypercalcemia, include nausea and vomiting, weakness, headache, somnolence, dry mouth, constipation, metallic taste, muscle pain and bone pain. Late symptoms and signs of hypercalcemia, include polyuria, polydipsia, anorexia, weight loss, nocturia, conjunctivitis, pancreatitis, photophobia, rhinorrhea, pruritis, hyperthermia, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated ALT (SGPT) and AST (SGOT), ectopic calcification, nephrocalcinosis, hypertension and cardiac arrhythmias.
Cyanocobalamin에 대한 Toxicity 정보
Anaphylactic reaction (skin rash, itching, wheezing)-after parenteral administration. ORL-MUS LD50 > 8000 mg/kg
Pyridoxine에 대한 Toxicity 정보
Oral Rat LD50 = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.
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| Drug Interactions |
Calcium에 대한 Drug_Interactions 정보
Alendronate Formation of non-absorbable complexesAmprenavir The antiacid decreases the absorption of amprenavirAtazanavir This gastric pH modifier decreases the levels/effects of atazanavirChloroquine The antiacid decreases the absorption of chloroquineCiprofloxacin Formation of non-absorbable complexesDapsone Formation of non-absorbable complexesDelavirdine The antiacid decreases the effect of delavirdineDemeclocycline Formation of non-absorbable complexesDoxycycline Formation of non-absorbable complexesEnoxacin Formation of non-absorbable complexesFosamprenavir The antiacid decreases the absorption of amprenavirGrepafloxacin Formation of non-absorbable complexesIbandronate Formation of non-absorbable complexesIndinavir The antiacid decreases the absorption of indinavirItraconazole The antacid decreases the effect of the imidazoleKetoconazole The antacid decreases the effect of the imidazoleLevofloxacin Formation of non-absorbable complexesLevothyroxine Calcium decreases absorption of levothyroxineLomefloxacin Formation of non-absorbable complexesMethacycline Formation of non-absorbable complexesMinocycline Formation of non-absorbable complexesMoxifloxacin Formation of non-absorbable complexesNorfloxacin Formation of non-absorbable complexesOfloxacin Formation of non-absorbable complexesOxytetracycline Formation of non-absorbable complexesPefloxacin Formation of non-absorbable complexesPolystyrene sulfonate Formation of non-absorbable complexesRisedronate Formation of non-absorbable complexesTetracycline Formation of non-absorbable complexesTrovafloxacin Formation of non-absorbable complexesClodronate Formation of non-absorbable complexesEtidronic acid Formation of non-absorbable complexesMycophenolate mofetil Formation of non-absorbable complexesTemafloxacin Formation of non-absorbable complexes
Cholecalciferol에 대한 Drug_Interactions 정보
Not Available
Cyanocobalamin에 대한 Drug_Interactions 정보
Not Available
calcium에 대한 Drug_Interactions 정보
Alendronate Formation of non-absorbable complexesAmprenavir The antiacid decreases the absorption of amprenavirAtazanavir This gastric pH modifier decreases the levels/effects of atazanavirChloroquine The antiacid decreases the absorption of chloroquineCiprofloxacin Formation of non-absorbable complexesDapsone Formation of non-absorbable complexesDelavirdine The antiacid decreases the effect of delavirdineDemeclocycline Formation of non-absorbable complexesDoxycycline Formation of non-absorbable complexesEnoxacin Formation of non-absorbable complexesFosamprenavir The antiacid decreases the absorption of amprenavirGrepafloxacin Formation of non-absorbable complexesIbandronate Formation of non-absorbable complexesIndinavir The antiacid decreases the absorption of indinavirItraconazole The antacid decreases the effect of the imidazoleKetoconazole The antacid decreases the effect of the imidazoleLevofloxacin Formation of non-absorbable complexesLevothyroxine Calcium decreases absorption of levothyroxineLomefloxacin Formation of non-absorbable complexesMethacycline Formation of non-absorbable complexesMinocycline Formation of non-absorbable complexesMoxifloxacin Formation of non-absorbable complexesNorfloxacin Formation of non-absorbable complexesOfloxacin Formation of non-absorbable complexesOxytetracycline Formation of non-absorbable complexesPefloxacin Formation of non-absorbable complexesPolystyrene sulfonate Formation of non-absorbable complexesRisedronate Formation of non-absorbable complexesTetracycline Formation of non-absorbable complexesTrovafloxacin Formation of non-absorbable complexesClodronate Formation of non-absorbable complexesEtidronic acid Formation of non-absorbable complexesMycophenolate mofetil Formation of non-absorbable complexesTemafloxacin Formation of non-absorbable complexes
Pyridoxine에 대한 Drug_Interactions 정보
Not Available
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CYP450
Drug Interaction |
[CYP450 Table직접조회]
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| Drug Target |
[Drug Target]
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| Description |
Calcium에 대한 Description 정보
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.
Cholecalciferol에 대한 Description 정보
Derivative of 7-dehydroxycholesterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from ergocalciferol in having a single bond between C22 and C23 and lacking a methyl group at C24. [PubChem]
Cyanocobalamin에 대한 Description 정보
Cyanocobalamin (commonly known as Vitamin B12) is the most chemically complex of all the vitamins. Cyanocobalamin's structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Cyanocobalamin cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Cyanocobalamin is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products. [HMDB]
calcium에 대한 Description 정보
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.
Nicotinamide에 대한 Description 정보
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]
Pyridoxine에 대한 Description 정보
The 4-methanol form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). [PubChem]
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| Dosage Form |
Calcium에 대한 Dosage_Form 정보
Capsule OralLiquid DentalLiquid IntravenousLiquid OralLiquid SublingualPaste DentalPowder OralPowder, for solution OralSolution IntramuscularSolution IntravenousSolution OralSolution / drops OralSyrup OralTablet OralTablet, chewable Oral
Cholecalciferol에 대한 Dosage_Form 정보
Capsule OralTablet Oral
Cyanocobalamin에 대한 Dosage_Form 정보
Capsule OralLiquid IntramuscularLiquid OralPowder OralSolution IntramuscularTablet OralTablet, extended release Oral
calcium에 대한 Dosage_Form 정보
Capsule OralLiquid DentalLiquid IntravenousLiquid OralLiquid SublingualPaste DentalPowder OralPowder, for solution OralSolution IntramuscularSolution IntravenousSolution OralSolution / drops OralSyrup OralTablet OralTablet, chewable Oral
Pyridoxine에 대한 Dosage_Form 정보
Liquid IntramuscularSolution IntramuscularSolution / drops OralTablet Oral
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| Drug Category |
Cholecalciferol에 대한 Drug_Category 정보
Antihypocalcemic AgentsAntihypoparathyroid AgentsBone Density Conservation AgentsEssential VitaminVitaminsVitamins (Vitamin D)
Cyanocobalamin에 대한 Drug_Category 정보
Antianemic AgentsEssential VitaminVitamins (Vitamin B Complex)
Nicotinamide에 대한 Drug_Category 정보
Vitamin B Complex
Pyridoxine에 대한 Drug_Category 정보
Anti-inflammatory AgentsEssential VitaminVitamin B ComplexVitamins (Vitamin B Complex)
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| Smiles String Canonical |
Calcium에 대한 Smiles_String_canonical 정보
Not Available
Cholecalciferol에 대한 Smiles_String_canonical 정보
CC(C)CCCC(C)C1CCC2C(CCCC12C)=CC=C1CC(O)CCC1=C
Cyanocobalamin에 대한 Smiles_String_canonical 정보
[Co+3].[C-]
calcium에 대한 Smiles_String_canonical 정보
Not Available
Nicotinamide에 대한 Smiles_String_canonical 정보
NC(=O)C1=CC=CN=C1
Pyridoxine에 대한 Smiles_String_canonical 정보
CC1=NC=C(CO)C(CO)=C1O
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| Smiles String Isomeric |
Calcium에 대한 Smiles_String_isomeric 정보
Not Available
Cholecalciferol에 대한 Smiles_String_isomeric 정보
CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CCC\C2=C/C=C1\C[C@@H](O)CCC1=C
Cyanocobalamin에 대한 Smiles_String_isomeric 정보
[Co+3].[C-]
calcium에 대한 Smiles_String_isomeric 정보
Not Available
Nicotinamide에 대한 Smiles_String_isomeric 정보
NC(=O)C1=CC=CN=C1
Pyridoxine에 대한 Smiles_String_isomeric 정보
CC1=NC=C(CO)C(CO)=C1O
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| InChI Identifier |
Calcium에 대한 InChI_Identifier 정보
Not Available
Cholecalciferol에 대한 InChI_Identifier 정보
InChI=1/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/t21-,24+,25-,26+,27-/m1/s1
Cyanocobalamin에 대한 InChI_Identifier 정보
InChI=1/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;-1;+3/p-1/t31?,34-,35-,36-,37+,41+,52?,53?,56?,57+,59-,60+,61+,62+;;/m1../s1/fC62H89N13O14P.CN.Co/h69,85H,63-68H2;;/q-1;2m/b42-23-,54-32-,55-33-;;
calcium에 대한 InChI_Identifier 정보
Not Available
Nicotinamide에 대한 InChI_Identifier 정보
InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)/f/h7H2
Pyridoxine에 대한 InChI_Identifier 정보
InChI=1/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
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| Chemical IUPAC Name |
Calcium에 대한 Chemical_IUPAC_Name 정보
Not Available
Cholecalciferol에 대한 Chemical_IUPAC_Name 정보
(1S)-3-[2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
Cyanocobalamin에 대한 Chemical_IUPAC_Name 정보
Not Available
calcium에 대한 Chemical_IUPAC_Name 정보
Not Available
Nicotinamide에 대한 Chemical_IUPAC_Name 정보
pyridine-3-carboxamide
Pyridoxine에 대한 Chemical_IUPAC_Name 정보
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
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| 사용자컨텐츠 |
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최근정보수정일 2016-05-10
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본 수정일 정보는 허가정보 이외의 기타정보 수정일을 의미하므로, 허가정보수정일은 본문에 표기된 날짜를 참조하시기 바랍니다.
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| 알림 |
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| 경고 |
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