드러그인포 약품요약정보

허가정보

항목

내용

청구코드(KD코드)
비급여점검코드
상한금액

비급여
[상병코드조회]
[질병코드조회]

빠른조회


요약정보	[효능] [용법] [금기] [신중투여] [이상반응]

상세정보	[효능] [용법] [경고] [금기] [신중투여] [이상반응] [일반주의] [상호작용] [임산부] [수유부] [소아] [고령자] [신장애환자] [간장애환자] [적용주의] [과량투여] [임상검사치] [보관] [기타]

제품성상

백색의 원형정제 [제형정보 확인]

효능효과

[적응증 별 검색]

동맥경화증 보조치료

용법용량

* 절대 임의복용하지 마시고 반드시 의사 또는 약사와 상담하시기 바랍니다.

[처방약어]
1일 2-3정을 3회로 분할하여 식사전에 물과 함께 복용한다.
환자에 따라 적의 증감할 것.

[BMI지수 계산] [Body Surface Area 계산] [Cockcroft-Gault GFR 계산] [MDRD GFR 계산]

금기

이약에 들어있는 각 주성분에 의해 과민반응이 나타난 적이 있는 사람

신중투여

중증질환, 알레르기, 다른질환의 치료를 위해 다른 약을 복용하고 있는 경우에는 의사 또는 약사와 상의할 것

이상반응

소화기 : 때때로 구토, 위통, 구강내 이상감등의 증상이 나타날 수 있다.

피부 : 때때로 발진등의 증상이 나타날 수 있다.

[주요 이상반응정보]

Off-label Usage

[조회]

정보요약

드럭인포 의약품 요약/상세정보

코드 및 분류정보

항목	내용
BIT 약효분류	순환개선제 (Circulatory Improvement Agents)
ATC 코드	Other peripheral vasodilators / C04AX [코드분류상세설명] [ATC코드예측]
복지부분류코드	219 (기타의 순환계용약 )
Drugs By Indication	[전체보기]
Drugs By Classification	[전체보기]

제품정보

항목	내용
청구코드(KD코드) 비급여점검코드 상한금액	비급여 [상병코드조회] [질병코드집 다운로드]
제품성상	백색의 원형정제 [제형정보 확인]
보관방법	밀폐용기, 실온보관

복약정보

항목	내용
LACTmed 바로가기	[바로가기]
약리작용	유료정보입니다.
복약지도	유료정보입니다.
Pharmacokinetics	유료정보입니다.
병용금기 및 연령대금기 근거조회	[병용금기 및 연령대금기 근거조회]
보관상 주의
조제시 주의

심사정보

항목	내용
DUR 관련 고시	[병용연령금기 의약품 / 임부금기 의약품 / 비용효과적 함량 의약품 / 안전성 관련 급여중지 의약품]

학술정보

항목	내용
DUR (의약품사용평가)	병용금기 : 고시된 병용금기 내용은 없습니다. [상호작용/병용금기검색] 연령대금기 : 고시된 연령금기 내용은 없습니다. [연령대금기상세검색]
독성정보	Ethanol에 대한 독성정보 : 정보보기 출처: 국립독성과학원 독성물질정보DB : http://www.nitr.go.kr/nitr/contents/m134200/view.do
Mechanism of Action	ethanol에 대한 Mechanism_Of_Action 정보 The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes. Ginseng에 대한 Mechanism_Of_Action 정보 Not Available Ethanol에 대한 Mechanism_Of_Action 정보 The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes.
Pharmacology	ethanol에 대한 Pharmacology 정보 Alcohol produces injury to cells by dehydration and precipitation of the cytoplasm or protoplasm. This accounts for its bacteriocidal and antifungal action. When alcohol is injected in close proximity to nerve tissues, it produces neuritis and nerve degeneration (neurolysis). Ninety to 98% of ethanol that enters the body is completely oxidized. Ethanol is also used as a cosolvent to dissolve many insoluble drugs and to serve as a mild sedative in some medicinal formulations. Ginseng에 대한 Pharmacology 정보 Not Available Ethanol에 대한 Pharmacology 정보 Alcohol produces injury to cells by dehydration and precipitation of the cytoplasm or protoplasm. This accounts for its bacteriocidal and antifungal action. When alcohol is injected in close proximity to nerve tissues, it produces neuritis and nerve degeneration (neurolysis). Ninety to 98% of ethanol that enters the body is completely oxidized. Ethanol is also used as a cosolvent to dissolve many insoluble drugs and to serve as a mild sedative in some medicinal formulations.
Metabolism	ethanol에 대한 Metabolism 정보 # Phase_1_Metabolizing_Enzyme:Cytochrome P450 2E1 (CYP2E1) Ginseng에 대한 Metabolism 정보 # Phase_1_Metabolizing_Enzyme:Cytochrome P450 1A1 (CYP1A1) Ethanol에 대한 Metabolism 정보 # Phase_1_Metabolizing_Enzyme:Cytochrome P450 2E1 (CYP2E1)
Half-life	ethanol에 대한 반감기 정보 Not Available Ginseng에 대한 반감기 정보 Not Available Ethanol에 대한 반감기 정보 Not Available
Absorption	ethanol에 대한 Absorption 정보 Rapidly absorbed. Ginseng에 대한 Absorption 정보 Not Available Ethanol에 대한 Absorption 정보 Rapidly absorbed.
Pharmacokinetics	Ginkgo Biloba Leaf Extract의 약물동력학자료 생체내이용률 : Ginko 경구 복용 후 Ginkgolide A : 98-100% Ginkgolide B : 79- 93% Bilobalide : 72% 반감기 : Ginko 경구 또는 정맥주사 후 Ginkgolide A 경구 : 3.9 시간 정맥주사 : 3.5 시간 Ginkgolide B 경구 : 7 시간 정맥주사 : 5.5 시간 Bilobalide 경구, 정맥주사 : 3.2 시간 Garlic extract 94%의 약물동력학자료 작용 발현 시간 : 초기 반응 : 항혈소판 응집 효과 : 경구 : 2-4 시간 고혈압 : 경구 : 5시간 고콜레스테롤혈증 : 1개월 작용 지속 시간 : 고혈압 : 14시간
Biotransformation	ethanol에 대한 Biotransformation 정보 Hepatic. Metabolized by cytochrome P450 enzyme CYP2E1. Ginseng에 대한 Biotransformation 정보 Not Available Ethanol에 대한 Biotransformation 정보 Hepatic. Metabolized by cytochrome P450 enzyme CYP2E1.
Toxicity	ethanol에 대한 Toxicity 정보 Oral, rat LD₅₀: 5628 mg/kg. Symptoms and effects of overdose include nausea, vomiting, CNS depression, acute respiratory failure or death and with chronic use, severe health problems, such as liver and brain damage. Ginseng에 대한 Toxicity 정보 Not Available Ethanol에 대한 Toxicity 정보 Oral, rat LD₅₀: 5628 mg/kg. Symptoms and effects of overdose include nausea, vomiting, CNS depression, acute respiratory failure or death and with chronic use, severe health problems, such as liver and brain damage.
Drug Interactions	ethanol에 대한 Drug_Interactions 정보 Not Available Ginseng에 대한 Drug_Interactions 정보 Amphetamine Decreased anorexic effect, may increase psychotic symptomsBenzphetamine Decreased anorexic effect, may increase psychotic symptomsDexfenfluramine Decreased anorexic effect, may increase psychotic symptomsDiethylpropion Decreased anorexic effect, may increase psychotic symptomsFenfluramine Decreased anorexic effect, may increase psychotic symptomsMazindol Decreased anorexic effect, may increase psychotic symptomsMethamphetamine Decreased anorexic effect, may increase psychotic symptomsPhendimetrazine Decreased anorexic effect, may increase psychotic symptomsDextroamphetamine Decreased anorexic effect, may increase psychotic symptomsPhenmetrazine Decreased anorexic effect, may increase psychotic symptomsPhentermine Decreased anorexic effect, may increase psychotic symptomsPhenylpropanolamine Decreased anorexic effect, may increase psychotic symptomsTranylcypromine Possible severe adverse reaction with this combinationPhenelzine Possible severe adverse reaction with this combinationIsocarboxazid Possible severe adverse reaction with this combinationPargyline Possible severe adverse reaction with this combinationBromocriptine The phenothiazine decreases the effect of bromocriptineCisapride Increased risk of cardiotoxicity and arrhythmiasGatifloxacin Increased risk of cardiotoxicity and arrhythmiasGrepafloxacin Increased risk of cardiotoxicity and arrhythmiasGuanethidine he agent decreases the effect of guanethidineLevofloxacin Increased risk of cardiotoxicity and arrhythmiasTerfenadine Increased risk of cardiotoxicity and arrhythmiasSparfloxacin Increased risk of cardiotoxicity and arrhythmiasRivastigmine Possible antagonism of actionDonepezil Possible antagonism of actionGalantamine Possible antagonism of actionMetrizamide Increased risk of convulsions Ethanol에 대한 Drug_Interactions 정보 Not Available
CYP450 Drug Interaction	[CYP450 Table직접조회] Ethanol에 대한 P450 table ethanol에 대한 P450 table SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid
Food Interaction	Ginseng에 대한 Food Interaction 정보 Not Available
Drug Target	[Drug Target]
Description	ethanol에 대한 Description 정보 A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. [PubChem] Ginseng에 대한 Description 정보 Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens. Ethanol에 대한 Description 정보 A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. [PubChem]
Dosage Form	ethanol에 대한 Dosage_Form 정보 Aerosol TopicalGel TopicalLiquid IntramuscularLiquid IntravenousLiquid OralLiquid TopicalLotion TopicalSolution TopicalSolution / drops OralSpray Topical Ginseng에 대한 Dosage_Form 정보 Capsule OralLiquid OralSolution / drops OralTablet Oral Ethanol에 대한 Dosage_Form 정보 Aerosol TopicalGel TopicalLiquid IntramuscularLiquid IntravenousLiquid OralLiquid TopicalLotion TopicalSolution TopicalSolution / drops OralSpray Topical
Drug Category	ethanol에 대한 Drug_Category 정보 Anti-Infective Agents, LocalCentral Nervous System DepressantsDisinfectantsSolvents Ginseng에 대한 Drug_Category 정보 Not Available Ethanol에 대한 Drug_Category 정보 Anti-Infective Agents, LocalCentral Nervous System DepressantsDisinfectantsSolvents
Smiles String Canonical	ethanol에 대한 Smiles_String_canonical 정보 CCO Ginseng에 대한 Smiles_String_canonical 정보 Not Available Ethanol에 대한 Smiles_String_canonical 정보 CCO
Smiles String Isomeric	ethanol에 대한 Smiles_String_isomeric 정보 CCO Ginseng에 대한 Smiles_String_isomeric 정보 Not Available Ethanol에 대한 Smiles_String_isomeric 정보 CCO
InChI Identifier	ethanol에 대한 InChI_Identifier 정보 Not Available Ginseng에 대한 InChI_Identifier 정보 Not Available Ethanol에 대한 InChI_Identifier 정보 Not Available
Chemical IUPAC Name	ethanol에 대한 Chemical_IUPAC_Name 정보 ethanol Ginseng에 대한 Chemical_IUPAC_Name 정보 Not Available Ethanol에 대한 Chemical_IUPAC_Name 정보 ethanol
Drug-Induced Toxicity Related Proteins	ETHANOL 의 Drug-Induced Toxicity Related Protein정보 Replated Protein:Proenkephalin Drug:ethanol Toxicity:ethanol narcosis. [바로가기] Replated Protein:Insulin receptor substrate 1 Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Phosphatidylinositol-4-phosphate 3-kinase Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Insulin receptor substrate 2 Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Mitogen-activated protein kinase(Erk2) Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Mitogen-activated protein kinase Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기]

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