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30º´, 60º´ |
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[ÀûÀÀÁõ º° °Ë»ö]
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[󹿾à¾î]
1ÀÏ 1~2º´À» º¹¿ëÇÒ °Í.
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- ¾Æ¹Ì³ë»ê ´ë»çÀå¾Ö ȯÀÚ(ƯÈ÷ ¼±Ãµ¼º È¿¼Ò °áÇÌ È¯ÀÚ)
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| Off-label Usage |
[Á¶È¸]
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| Related FDA Approved Drug |
±âÁØ ¼ººÐ: FOLIC ACIDBEROCCA PN (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A PALMITATE; VITAMIN E)
CERNEVIT-12 (ALPHA-TOCOPHEROL; ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; FOLIC ACID; NIACINAMIDE; PANTOTHENIC ACID; PYRIDOXINE; RIBOFLAVIN; THIAMINE; VITAMIN A)
FOLIC ACID (FOLIC ACID)
FOLICET (FOLIC ACID)
FOLVITE (FOLIC ACID)
FOLVRON (FERROUS SULFATE; FOLIC ACID)
INFUVITE ADULT (ALPHA-TOCOPHEROL ACETATE; ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A PALMITATE; VITAMIN K)
INFUVITE PEDIATRIC (ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K)
INFUVITE PEDIATRIC (PHARMACY BULK PACKAGE) (ASCORBIC ACID; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K)
M.V.C. 9+3 (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I. ADULT (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E; VITAMIN K)
M.V.I. ADULT (PHARMACY BULK PACKAGE) (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E; VITAMIN K)
M.V.I. PEDIATRIC (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I.-12 (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I.-12 (WITHOUT VITAMIN K) (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
M.V.I.-12 LYOPHILIZED (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE; VITAMIN A; VITAMIN E)
MVC PLUS (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E)
VITAPED (ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PANTOTHENIC ACID; PHYTONADIONE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; VITAMIN A PALMITATE; VITAMIN E)
±âÁØ ¼ººÐ: CYANOCOBALAMINBERUBIGEN (CYANOCOBALAMIN)
BETALIN 12 (CYANOCOBALAMIN)
CALOMIST (CYANOCOBALAMIN)
COBAVITE (CYANOCOBALAMIN)
CYANOCOBALAMIN (CYANOCOBALAMIN)
CYANOCOBALAMIN CO 57 SCHILLING TEST KIT (CYANOCOBALAMIN; CYANOCOBALAMIN, CO-57; INTRINSIC FACTOR)
DEPINAR (CYANOCOBALAMIN; TANNIC ACID; ZINC ACETATE)
DICOPAC KIT (CYANOCOBALAMIN; CYANOCOBALAMIN, CO-57; CYANOCOBALAMIN, CO-58)
NASCOBAL (CYANOCOBALAMIN)
REDISOL (CYANOCOBALAMIN)
RUBIVITE (CYANOCOBALAMIN)
RUBRAMIN PC (CYANOCOBALAMIN)
RUBRATOPE-57 (CYANOCOBALAMIN, CO-57)
RUBRATOPE-57 KIT (COBALT CHLORIDE, CO-57; CYANOCOBALAMIN; CYANOCOBALAMIN, CO-57; INTRINSIC FACTOR)
RUBRATOPE-60 (CYANOCOBALAMIN, CO-60)
RUBRATOPE-60 KIT (COBALT CHLORIDE, CO-60; CYANOCOBALAMIN; CYANOCOBALAMIN, CO-60; INTRINSIC FACTOR)
RUVITE (CYANOCOBALAMIN)
VIBISONE (CYANOCOBALAMIN)
VI-TWEL (CYANOCOBALAMIN)
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´ãÁó»êºÐºñÃËÁøÁ¦ & °£º¸È£Á¦ (Cholelitholitics & Hepatic Protectors)
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Vitamin B-complex, other combinations / A11EX
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[ATCÄÚµå¿¹Ãø]
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| º¹ÁöºÎºÐ·ùÄÚµå |
114 (ÇØ¿¡¤ÁøÅ롤¼Ò¿°Á¦ )
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| Drugs By Indication |
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À¯·áÁ¤º¸ÀÔ´Ï´Ù.
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ÀüüÀӽŠ±â°£º°·Î ¿©·¯µî±ÞÀÌ Á¸ÀçÇÒ ¼ö ÀÖÀ¸¸ç °¡Àå À§Çèµµ°¡ ³ôÀº Á¤º¸¸¸ º¸¿©Áý´Ï´Ù. ´Ü, º¹ÇÕÁ¦ÀÇ °æ¿ì ¸ðµç º¹ÇÕÁ¦¼ººÐ¿¡ ´ëÇÑ ÀÓºÎÅõ¿©µî±ÞÀÌ Ç¥½ÃµÈ°ÍÀº Àý´ë ¾Æ´Ï¸ç Ç¥½ÃµÈ°ÍÁß¿¡ °¡Àå À§Çèµµ°¡ ³ôÀº Á¤º¸¸¸ ³ªÅ¸³³´Ï´Ù.
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(cyanocobalamin;folic acid; )
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»ó±â ÀÓºÎÅõ¿©¿¡ ´ëÇÑ Á¤º¸´Â Àü»êó¸® µÇ¸é¼ ÀÔ·Â ¿À·ù °¡´É¼ºÀÌ Á¸ÀçÇÕ´Ï´Ù. ¿À·ù °¡´É¼ºÀ» ÃÖ¼ÒÈÇϱâ À§ÇÏ¿© ¸¹Àº ³ë·ÂÀ» ±â¿ïÀ̰í ÀÖÀ¸³ª, ±× Á¤È®¼º¿¡ ´ëÇÏ¿© È®½ÅÀ» µå¸± ¼ö ¾ø½À´Ï´Ù. ÀÌ¿¡ ´ëÇØ ȸ»ç´Â Ã¥ÀÓÀ» ÁöÁö ¾Ê½À´Ï´Ù.
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À¯·áÁ¤º¸ÀÔ´Ï´Ù.
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[º´¿ë±Ý±â ¹× ¿¬·É´ë±Ý±â ±Ù°ÅÁ¶È¸]
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| DUR (ÀǾàǰ»ç¿ëÆò°¡) |
º´¿ë±Ý±â :
°í½ÃµÈ º´¿ë±Ý±â ³»¿ëÀº ¾ø½À´Ï´Ù.
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Cyanocobalamin¿¡ ´ëÇÑ µ¶¼ºÁ¤º¸ : Á¤º¸º¸±â
Folic acid¿¡ ´ëÇÑ µ¶¼ºÁ¤º¸ : Á¤º¸º¸±â
Nicotinamide¿¡ ´ëÇÑ µ¶¼ºÁ¤º¸ : Á¤º¸º¸±â
Ãâó: ±¹¸³µ¶¼º°úÇпø µ¶¼º¹°ÁúÁ¤º¸DB : http://www.nitr.go.kr/nitr/contents/m134200/view.do |
| Mechanism of Action |
Cyanocobalamin¿¡ ´ëÇÑ Mechanism_Of_Action Á¤º¸ Vitamin B12 is used in the body in two forms: Methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells.
L-Citrulline¿¡ ´ëÇÑ Mechanism_Of_Action Á¤º¸ L-citrulline is converted to L-arginine by argininosuccinate synthase. L-arginine is in turn responsible for citrulline's therapeutic affects. Many of L-arginine's activities, including its possible anti-atherogenic actions, may be accounted for by its role as the precursor to nitric oxide or NO. NO is produced by all tissues of the body and plays very important roles in the cardiovascular system, immune system and nervous system. NO is formed from L-arginine via the enzyme nitric oxide synthase or synthetase (NOS), and the effects of NO are mainly mediated by 3',5' -cyclic guanylate or cyclic GMP. NO activates the enzyme guanylate cyclase, which catalyzes the synthesis of cyclic GMP from guanosine triphosphate or GTP. Cyclic GMP is converted to guanylic acid via the enzyme cyclic GMP phosphodiesterase.
NOS is a heme-containing enzyme with some sequences similar to cytochrome P-450 reductase. Several isoforms of NOS exist, two of which are constitutive and one of which is inducible by immunological stimuli. The constitutive NOS found in the vascular endothelium is designated eNOS and that present in the brain, spinal cord and peripheral nervous system is designated nNOS. The form of NOS induced by immunological or inflammatory stimuli is known as iNOS. iNOS may be expressed constitutively in select tissues such as lung epithelium.
All the nitric oxide synthases use NADPH (reduced nicotinamide adenine dinucleotide phosphate) and oxygen (O2) as cosubstrates, as well as the cofactors FAD (flavin adenine dinucleotide), FMN (flavin mononucleotide), tetrahydrobiopterin and heme. Interestingly, ascorbic acid appears to enhance NOS activity by increasing intracellular tetrahydrobiopterin. eNOS and nNOS synthesize NO in response to an increased concentration of calcium ions or in some cases in response to calcium-independent stimuli, such as shear stress. In vitro studies of NOS indicate that the Km of the enzyme for L-arginine is in the micromolar range. The concentration of L-arginine in endothelial cells, as well as in other cells, and in plasma is in the millimolar range. What this means is that, under physiological conditions, NOS is saturated with its L-arginine substrate. In other words, L-arginine would not be expected to be rate-limiting for the enzyme, and it would not appear that supraphysiological levels of L-arginine which could occur with oral supplementation of the amino acid would make any difference with regard to NO production. The reaction would appear to have reached its maximum level. However, in vivo studies have demonstrated that, under certain conditions, e.g. hypercholesterolemia, L-arginine could enhance endothelial-dependent vasodilation and NO production.
L-ornithine¿¡ ´ëÇÑ Mechanism_Of_Action Á¤º¸ L-Ornithine is metabolised to L-arginine. L-arginine stimulates the pituitary release of growth hormone. Burns or other injuries affect the state of L-arginine in tissues throughout the body. As De novo synthesis of L-arginine during these conditions is usually not sufficient for normal immune function, nor for normal protein synthesis, L-ornithine may have immunomodulatory and wound-healing activities under these conditions (by virtue of its metabolism to L-arginine).
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| Pharmacology |
Cyanocobalamin¿¡ ´ëÇÑ Pharmacology Á¤º¸ Cyanocobalamin (Vitamin B12) is a water-soluble organometallic compound with a trivalent cobalt ion bound inside a corrin ring. It is needed for nerve cells and red blood cells, and to make DNA. Vitamin B12 deficiency is the cause of several forms of anemia.
L-Citrulline¿¡ ´ëÇÑ Pharmacology Á¤º¸ A non-essential amino acid and a precursor of arginine. Citrulline supplements have been claimed to promote energy levels, stimulate the immune system and help detoxify ammonia (a cell toxin). L-citrulline is made from L-ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from L-arginine as a by-product of the reaction catalyzed by the enzyme NO synthase. L-citrulline, while being an amino acid, is not involved in protein synthesis and is not one of the amino acids coded for by DNA. Although citrulline cannot be incorporated in proteins during protein synthesis, several proteins are known to contain citrulline as an amino acid. These citrulline residues are generated by a family of enzymes called peptidylarginine deiminases (PADs), which convert the amino acid arginine into citrulline. Proteins that contain citrulline residues include myelin basic protein (MBP), fillagrin and several histone proteins.
L-ornithine¿¡ ´ëÇÑ Pharmacology Á¤º¸ A non-essential and nonprotein amino acid, ornithine is critical for the production of the body's proteins, enzymes and muscle tissue. Ornithine plays a central role in the urea cycle and is important for the disposal of excess nitrogen (ammonia). Ornithine is the starting point for the synthesis of many polyamines such as putrescine and spermine. Ornithine supplements are claimed to enhance the release of growth hormone and to burn excess body fat. Ornithine is necessary for proper immune function and good liver function.
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| Metabolism |
Cyanocobalamin¿¡ ´ëÇÑ Metabolism Á¤º¸ # Phase_1_Metabolizing_Enzyme:Methylenetetrahydrofolate reductase
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| Protein Binding |
Cyanocobalamin¿¡ ´ëÇÑ ´Ü¹é°áÇÕ Á¤º¸ Very high (to specific plasma proteins called transcobalamins); binding of hydroxocobalamin is slightly higher than cyanocobalamin.
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| Half-life |
Cyanocobalamin¿¡ ´ëÇÑ ¹Ý°¨±â Á¤º¸ Approximately 6 days (400 days in the liver).
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| Absorption |
Cyanocobalamin¿¡ ´ëÇÑ Absorption Á¤º¸ Readily absorbed in the lower half of the ileum.
L-ornithine¿¡ ´ëÇÑ Absorption Á¤º¸ Absorbed from the small intestine via a sodium-dependent active transport process
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| Pharmacokinetics |
NicotinamideÀÇ ¾à¹°µ¿·ÂÇÐÀÚ·á
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CyanocobalaminÀÇ ¾à¹°µ¿·ÂÇÐÀÚ·á
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- ºÐÆ÷ :
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- Àå°ü Á¡¸·¼¼Æ÷ ³»¿¡¼ vitamin B12-IF º¹ÇÕü·ÎºÎÅÍ vitamin B12°¡ À¯¸®µÈ ÈÄ, Ç÷¾× ³»¿¡¼ ÁַΠƯÀÌÀûÀÎ ¥â-globulin ¼ö¼Û´Ü¹éÁúÀÎ transcobalamin II¿Í °áÇÕÇÑ´Ù.
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- ´Ü¹é°áÇÕ : ÁÖ·Î transcobalamin II¿Í °áÇÕÇϸç, ¼Ò·®Àº transcobalamin I (¥á-glycoproteinÀÇ ÀÏÁ¾) ¹× transcobalamin III (inter-¥á-glycoproteinÀÇ ÀÏÁ¾)°ú °áÇÕÇÑ´Ù.
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- Vitamin B12¸¦ Åõ¿©¹Þ´Â °æ¿ì : 0.1-1 mg ±ÙÀ°ÁÖ»ç ¶Ç´Â Á¤¸ÆÁÖ»ç ÈÄ 48½Ã°£ À̳»¿¡ 50-90%°¡ ½Å¹è¼³µÈ´Ù.
Folic AcidÀÇ ¾à¹°µ¿·ÂÇÐÀÚ·á
- ÃÖ°íÈ¿°ú ¹ßÇö½Ã°£ : 0.5-1½Ã°£ ³»·Î ³ªÅ¸³´Ù.
- Èí¼ö : ¼ÒÀåÀÇ ±ÙÀ§ºÎºÐ(proximal part)¿¡¼ ÀÌ·ç¾îÁø´Ù.
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| Biotransformation |
Cyanocobalamin¿¡ ´ëÇÑ Biotransformation Á¤º¸ Hepatic
L-ornithine¿¡ ´ëÇÑ Biotransformation Á¤º¸ Ornithine undergoes extensive metabolism in the liver to L-arginine, polyamines, and proline, and several other metabolites.
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| Toxicity |
Cyanocobalamin¿¡ ´ëÇÑ Toxicity Á¤º¸ Anaphylactic reaction (skin rash, itching, wheezing)-after parenteral administration. ORL-MUS LD50 > 8000 mg/kg
L-ornithine¿¡ ´ëÇÑ Toxicity Á¤º¸ Oral, rat LD50 = 10000 mg/kg
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| Drug Interactions |
Cyanocobalamin¿¡ ´ëÇÑ Drug_Interactions Á¤º¸ Not Available
L-ornithine¿¡ ´ëÇÑ Drug_Interactions Á¤º¸ Not Available
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CYP450 Drug Interaction |
[CYP450 TableÁ÷Á¢Á¶È¸]
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| Drug Target |
[Drug Target]
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| Description |
Cyanocobalamin¿¡ ´ëÇÑ Description Á¤º¸ Cyanocobalamin (commonly known as Vitamin B12) is the most chemically complex of all the vitamins. Cyanocobalamin's structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Cyanocobalamin cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Cyanocobalamin is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products. [HMDB]
L-Citrulline¿¡ ´ëÇÑ Description Á¤º¸ Citrulline is an amino acid. It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.
L-ornithine¿¡ ´ëÇÑ Description Á¤º¸ Ornithine is an amino acid produced in the urea cycle by the splitting off of urea from arginine. It is a central part of the urea cycle, which allows for the disposal of excess nitrogen. L-Ornithine is a precursor of citrulline and arginine.
Nicotinamide¿¡ ´ëÇÑ Description Á¤º¸ An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]
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| Dosage Form |
Cyanocobalamin¿¡ ´ëÇÑ Dosage_Form Á¤º¸ Capsule OralLiquid IntramuscularLiquid OralPowder OralSolution IntramuscularTablet OralTablet, extended release Oral
L-Citrulline¿¡ ´ëÇÑ Dosage_Form Á¤º¸ Not Available
L-ornithine¿¡ ´ëÇÑ Dosage_Form Á¤º¸ Capsule OralCapsule OralCapsule OralCapsule OralPowder Oral
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| Drug Category |
Cyanocobalamin¿¡ ´ëÇÑ Drug_Category Á¤º¸ Antianemic AgentsEssential VitaminVitamins (Vitamin B Complex)
L-Citrulline¿¡ ´ëÇÑ Drug_Category Á¤º¸ Dietary supplementMicronutrientNon-Essential Amino Acids
Nicotinamide¿¡ ´ëÇÑ Drug_Category Á¤º¸ Vitamin B Complex
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| Smiles String Canonical |
Cyanocobalamin¿¡ ´ëÇÑ Smiles_String_canonical Á¤º¸ [Co+3].[C-]
L-Citrulline¿¡ ´ëÇÑ Smiles_String_canonical Á¤º¸ NC(CCCNC(N)=O)C(O)=O
L-ornithine¿¡ ´ëÇÑ Smiles_String_canonical Á¤º¸ NCCCC(N)C(O)=O
Nicotinamide¿¡ ´ëÇÑ Smiles_String_canonical Á¤º¸ NC(=O)C1=CC=CN=C1
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| Smiles String Isomeric |
Cyanocobalamin¿¡ ´ëÇÑ Smiles_String_isomeric Á¤º¸ [Co+3].[C-]
L-Citrulline¿¡ ´ëÇÑ Smiles_String_isomeric Á¤º¸ N[C@@H](CCCNC(N)=O)C(O)=O
L-ornithine¿¡ ´ëÇÑ Smiles_String_isomeric Á¤º¸ NCCC[C@H](N)C(O)=O
Nicotinamide¿¡ ´ëÇÑ Smiles_String_isomeric Á¤º¸ NC(=O)C1=CC=CN=C1
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| InChI Identifier |
Cyanocobalamin¿¡ ´ëÇÑ InChI_Identifier Á¤º¸ InChI=1/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;-1;+3/p-1/t31?,34-,35-,36-,37+,41+,52?,53?,56?,57+,59-,60+,61+,62+;;/m1../s1/fC62H89N13O14P.CN.Co/h69,85H,63-68H2;;/q-1;2m/b42-23-,54-32-,55-33-;;
L-Citrulline¿¡ ´ëÇÑ InChI_Identifier Á¤º¸ InChI=1/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1/f/h9-10H,8H2
L-ornithine¿¡ ´ëÇÑ InChI_Identifier Á¤º¸ InChI=1/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1/f/h8H
Nicotinamide¿¡ ´ëÇÑ InChI_Identifier Á¤º¸ InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)/f/h7H2
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| Chemical IUPAC Name |
Cyanocobalamin¿¡ ´ëÇÑ Chemical_IUPAC_Name Á¤º¸ Not Available
L-Citrulline¿¡ ´ëÇÑ Chemical_IUPAC_Name Á¤º¸ (2S)-2-amino-5-(carbamoylamino)pentanoic acid
L-ornithine¿¡ ´ëÇÑ Chemical_IUPAC_Name Á¤º¸ (2S)-2,5-diaminopentanoic acid
Nicotinamide¿¡ ´ëÇÑ Chemical_IUPAC_Name Á¤º¸ pyridine-3-carboxamide
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µå·°ÀÎÆ÷ ÀǾàÇмúÁ¤º¸´Â ½ÄǰÀǾàǰ¾ÈÀüóÀÇ Á¦Ç°Çã°¡»çÇ×, Çмú¹®Çå, Á¦¾àȸ»ç Á¦°øÁ¤º¸ µîÀ» ±Ù°Å·Î ÀÛ¼ºµÈ Âü°í Á¤º¸ÀÔ´Ï´Ù.
Á¤º¸ÀÇ Á¤È®¼ºÀ» À§ÇØ ³ë·ÂÇϰí ÀÖÀ¸³ª ÆíÁý»óÀÇ ¿À·ù, Çã°¡»çÇ× º¯°æ, Ãß°¡ÀûÀÎ Çмú¿¬±¸ ¶Ç´Â Àӻ󿬱¸ ¹ßÇ¥ µîÀ¸·Î ÀÎÇØ ¹ß»ýÇÏ´Â ¹®Á¦¿¡ ´ëÇØ µå·°ÀÎÆ÷´Â
Ã¥ÀÓÀ» ÁöÁö ¾Ê½À´Ï´Ù. ÀÚ¼¼ÇÑ ³»¿ëÀº ¡°Ã¥ÀÓÀÇ ÇÑ°è ¹× ¹ýÀû°íÁö¡±¸¦ ÂüÁ¶ÇØ ÁֽʽÿÀ.
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ÀüÈ: 02-3486-1061 ¤Ó À̸ÞÀÏ: webmaster@druginfo.co.kr
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