드러그인포 약품요약정보

허가정보

항목

내용

청구코드(KD코드)
비급여점검코드
상한금액

645303740[A37801821] [보험코드에 따른 약품기본정보 직접조회]
\0 원/1개(2006.05.01)(현재약가)
\171 원/1개(2001.09.20)(변경전약가)
[상병코드조회]
[질병코드조회]

빠른조회


요약정보	[효능] [용법] [금기] [신중투여] [이상반응]

상세정보	[효능] [용법] [경고] [금기] [신중투여] [이상반응] [일반주의] [상호작용] [임산부] [수유부] [소아] [고령자] [신장애환자] [간장애환자] [적용주의] [과량투여] [임상검사치] [보관] [기타]

제품성상

연한 갈색의 균질한 좌제 [제형정보 확인]

포장·유통단위

10S

허가사항 원문조회

[허가사항 원문조회]

효능효과

[적응증 별 검색]

치질과 관련된 열상, 궤양, 염증등의 완화
[Drugbank 의 성분정보열람]
[Ethanol]

용법용량

* 절대 임의복용하지 마시고 반드시 의사 또는 약사와 상담하시기 바랍니다.

[처방약어]
[주성분코드:413800CSP 에 따른 심사지침열람]
의사의 지시가 없는한 매 배변후 및 취침전 1 좌제를 직장에 삽입한다 .
[제형별복약지도]

[BMI지수 계산] [Body Surface Area 계산] [Cockcroft-Gault GFR 계산] [MDRD GFR 계산]

신중투여

지금까지 약에 의해 알레르기 증상 (발진, 발적, 가려움증 , 부종 등)을 일으킨 적이 있는 사람의사의 치료를 받고 있는 사람

Off-label Usage

[조회]

정보요약

드럭인포 의약품 요약/상세정보

코드 및 분류정보

항목	내용
대표코드	8806453037400
BIT 약효분류	혈관강화제, 정맥류 치료제, 치질약(Capillary stabilizer, Phlebitis, Varicose veins, Hemorrhoidal)
ATC 코드	Other agents for treatment of hemorrhoids and anal fissures for topical use / C05AX [코드분류상세설명] [ATC코드예측]
복지부분류코드	256 (치질용제 )
주성분코드 분석 및 중복처방 검토	[주성분코드 분석 및 중복처방 검토]
Drugs By Indication	[전체보기]
Drugs By Classification	[전체보기]

제품정보

항목	내용
청구코드(KD코드) 비급여점검코드 상한금액	645303740[A37801821] [보험코드에 따른 약품기본정보 직접조회] \0 원/1개(2006.05.01)(최신약가) \171 원/1개(2001.09.20)(변경전약가) [상병코드조회] [질병코드집 다운로드]
제품성상	연한 갈색의 균질한 좌제 [제형정보 확인]
포장·유통단위	10S
보관방법	기밀용기,냉암소보관
동일주성분코드 검색순위	유료정보입니다.

복약정보

항목	내용
LACTmed 바로가기	[바로가기]
약리작용	유료정보입니다.
병용금기 및 연령대금기 근거조회	[병용금기 및 연령대금기 근거조회]
제형별 복약지도	[좌제]
보관상 주의
조제시 주의

심사정보

항목	내용
DUR 관련 고시	[병용연령금기 의약품 / 임부금기 의약품 / 비용효과적 함량 의약품 / 안전성 관련 급여중지 의약품]

학술정보

항목	내용
DUR (의약품사용평가)	병용금기 : 고시된 병용금기 내용은 없습니다. [상호작용/병용금기검색] 연령대금기 : 고시된 연령금기 내용은 없습니다. [연령대금기상세검색]
독성정보	Ethanol에 대한 독성정보 : 정보보기 출처: 국립독성과학원 독성물질정보DB : http://www.nitr.go.kr/nitr/contents/m134200/view.do
Mechanism of Action	ethanol에 대한 Mechanism_Of_Action 정보 The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes. Ethanol에 대한 Mechanism_Of_Action 정보 The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes.
Pharmacology	ethanol에 대한 Pharmacology 정보 Alcohol produces injury to cells by dehydration and precipitation of the cytoplasm or protoplasm. This accounts for its bacteriocidal and antifungal action. When alcohol is injected in close proximity to nerve tissues, it produces neuritis and nerve degeneration (neurolysis). Ninety to 98% of ethanol that enters the body is completely oxidized. Ethanol is also used as a cosolvent to dissolve many insoluble drugs and to serve as a mild sedative in some medicinal formulations. Ethanol에 대한 Pharmacology 정보 Alcohol produces injury to cells by dehydration and precipitation of the cytoplasm or protoplasm. This accounts for its bacteriocidal and antifungal action. When alcohol is injected in close proximity to nerve tissues, it produces neuritis and nerve degeneration (neurolysis). Ninety to 98% of ethanol that enters the body is completely oxidized. Ethanol is also used as a cosolvent to dissolve many insoluble drugs and to serve as a mild sedative in some medicinal formulations.
Metabolism	ethanol에 대한 Metabolism 정보 # Phase_1_Metabolizing_Enzyme:Cytochrome P450 2E1 (CYP2E1) Ethanol에 대한 Metabolism 정보 # Phase_1_Metabolizing_Enzyme:Cytochrome P450 2E1 (CYP2E1)
Half-life	ethanol에 대한 반감기 정보 Not Available Ethanol에 대한 반감기 정보 Not Available
Absorption	ethanol에 대한 Absorption 정보 Rapidly absorbed. Ethanol에 대한 Absorption 정보 Rapidly absorbed.
Biotransformation	ethanol에 대한 Biotransformation 정보 Hepatic. Metabolized by cytochrome P450 enzyme CYP2E1. Ethanol에 대한 Biotransformation 정보 Hepatic. Metabolized by cytochrome P450 enzyme CYP2E1.
Toxicity	ethanol에 대한 Toxicity 정보 Oral, rat LD₅₀: 5628 mg/kg. Symptoms and effects of overdose include nausea, vomiting, CNS depression, acute respiratory failure or death and with chronic use, severe health problems, such as liver and brain damage. Ethanol에 대한 Toxicity 정보 Oral, rat LD₅₀: 5628 mg/kg. Symptoms and effects of overdose include nausea, vomiting, CNS depression, acute respiratory failure or death and with chronic use, severe health problems, such as liver and brain damage.
Drug Interactions	ethanol에 대한 Drug_Interactions 정보 Not Available Ethanol에 대한 Drug_Interactions 정보 Not Available
CYP450 Drug Interaction	[CYP450 Table직접조회] Ethanol에 대한 P450 table ethanol에 대한 P450 table SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid SUBSTRATES CYP 2E1 acetaminophen chlorzoxazone ethanol INHIBITORS CYP 2E1 disulfiram INDUCERS CYP 2E1 ethanol isoniazid
Drug Target	[Drug Target]
Description	ethanol에 대한 Description 정보 A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. [PubChem] Ethanol에 대한 Description 정보 A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. [PubChem]
Dosage Form	ethanol에 대한 Dosage_Form 정보 Aerosol TopicalGel TopicalLiquid IntramuscularLiquid IntravenousLiquid OralLiquid TopicalLotion TopicalSolution TopicalSolution / drops OralSpray Topical Ethanol에 대한 Dosage_Form 정보 Aerosol TopicalGel TopicalLiquid IntramuscularLiquid IntravenousLiquid OralLiquid TopicalLotion TopicalSolution TopicalSolution / drops OralSpray Topical
Drug Category	ethanol에 대한 Drug_Category 정보 Anti-Infective Agents, LocalCentral Nervous System DepressantsDisinfectantsSolvents Ethanol에 대한 Drug_Category 정보 Anti-Infective Agents, LocalCentral Nervous System DepressantsDisinfectantsSolvents
Smiles String Canonical	ethanol에 대한 Smiles_String_canonical 정보 CCO Ethanol에 대한 Smiles_String_canonical 정보 CCO
Smiles String Isomeric	ethanol에 대한 Smiles_String_isomeric 정보 CCO Ethanol에 대한 Smiles_String_isomeric 정보 CCO
InChI Identifier	ethanol에 대한 InChI_Identifier 정보 Not Available Ethanol에 대한 InChI_Identifier 정보 Not Available
Chemical IUPAC Name	ethanol에 대한 Chemical_IUPAC_Name 정보 ethanol Ethanol에 대한 Chemical_IUPAC_Name 정보 ethanol
Drug-Induced Toxicity Related Proteins	ALCOHOL 의 Drug-Induced Toxicity Related Protein정보 Replated Protein:Pancreatitis associated protein Drug:alcohol Toxicity:regular subclinical pancreatic damage. [바로가기] Replated Protein:Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) Drug:alcohol Toxicity:mitochondrial glutathione depletion. [바로가기] Replated Protein:Proto-oncogene protein c-fos Drug:alcohol Toxicity:alcohol intoxication. [바로가기] Replated Protein:Opioid growth factor receptor Drug:alcohol Toxicity:alcohol intoxication. [바로가기] Replated Protein:Glutathione S-transferase Mu 1 Drug:alcohol Toxicity:chronic pancreatitis (CP). [바로가기] Replated Protein:D(2) dopamine receptor Drug:alcohol Toxicity:chronic pancreatitis. [바로가기] Replated Protein:Signal transducer and activator of transcription 3 (Sta3) Drug:alcohol Toxicity:alcohol intoxication. [바로가기] Replated Protein:Proto-oncogene protein c-fos Drug:alcohol Toxicity:alcohol intoxication. [바로가기] Replated Protein:Myeloperoxidase Drug:alcohol Toxicity:acute pancreatitis. [바로가기] Replated Protein:Mitogen-activated protein kinase Drug:alcohol Toxicity:alcohol intoxication. [바로가기] Replated Protein:Extracellular signal-regulated kinase Drug:alcohol Toxicity:alcohol intoxication. [바로가기] Replated Protein:Parathyroid hormone Drug:alcohol Toxicity:hyperparathyroidism. [바로가기] Replated Protein:carbohydrate-deficient serotransferrin (??) Drug:alcohol Toxicity:alcohol abuse. [바로가기] ALCOHOL(ETOH) 의 Drug-Induced Toxicity Related Protein정보 Replated Protein:Insulin Drug:alcohol(EtOH) Toxicity:impairs insulin. [바로가기] Replated Protein:Eukaryotic translation initiation factor 4E-binding protein Drug:alcohol(EtOH) Toxicity:impairs insulin. [바로가기] Replated Protein:Eukaryotic translation initiation factor 4E Drug:alcohol(EtOH) Toxicity:impairs insulin. [바로가기] ETHANOL 의 Drug-Induced Toxicity Related Protein정보 Replated Protein:Proenkephalin Drug:ethanol Toxicity:ethanol narcosis. [바로가기] Replated Protein:Insulin receptor substrate 1 Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Phosphatidylinositol-4-phosphate 3-kinase Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Insulin receptor substrate 2 Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Mitogen-activated protein kinase(Erk2) Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기] Replated Protein:Mitogen-activated protein kinase Drug:Ethanol Toxicity:impair liver regeneration, inhibit DNA synthesis, and mute cellular responses to growth factor stimulation. [바로가기]

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항목

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